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Kelly Grimes
Kelly Grimes
Verified email at cchmc.org
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Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy
D Vanhoutte, TG Schips, A Vo, KM Grimes, TA Baldwin, MJ Brody, ...
Nature Communications 12 (1), 3928, 2021
772021
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity
JC Triplett, A Tramutola, A Swomley, J Kirk, K Grimes, K Lewis, M Orr, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (10 …, 2015
722015
ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity
JG Boyer, V Prasad, T Song, D Lee, X Fu, KM Grimes, MA Sargent, ...
JCI insight 4 (10), 2019
642019
Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent
KA Rodriguez, E Wywial, VI Perez, AJ Lambert, YH Edrey, KN Lewis, ...
Current pharmaceutical design 17 (22), 2290, 2011
622011
And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat
KM Grimes, AK Reddy, ML Lindsey, R Buffenstein
American Journal of Physiology-Heart and Circulatory Physiology 307 (3 …, 2014
542014
MCUb induction protects the heart from postischemic remodeling
J Huo, S Lu, JQ Kwong, MJ Bround, KM Grimes, MA Sargent, ME Brown, ...
Circulation research 127 (3), 379-390, 2020
492020
Cardiac function of the naked mole-rat: ecophysiological responses to working underground
KM Grimes, A Voorhees, YA Chiao, HC Han, ML Lindsey, R Buffenstein
American Journal of Physiology-Heart and Circulatory Physiology 306 (5 …, 2014
442014
Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat
KM Grimes, ML Lindsey, JAL Gelfond, R Buffenstein
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012
442012
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury
JA Schwanekamp, A Lorts, MA Sargent, AJ York, KM Grimes, ...
PloS one 12 (7), e0181945, 2017
412017
Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart
RN Correll, KM Grimes, V Prasad, JM Lynch, H Khalil, JD Molkentin
Scientific reports 9 (1), 2059, 2019
332019
Probing pedomorphy and prolonged lifespan in naked mole-rats and dwarf mice
R Buffenstein, KN Lewis, PA Gibney, V Narayan, KM Grimes, M Smith, ...
Physiology 35 (2), 96-111, 2020
292020
Supporting the heart: Functions of the cardiomyocyte's non-sarcomeric cytoskeleton
KM Grimes, V Prasad, JW McNamara
Journal of molecular and cellular cardiology 131, 187-196, 2019
292019
The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent
KM Grimes, DY Barefield, M Kumar, JW McNamara, ST Weintraub, ...
Pflügers Archiv-European Journal of Physiology 469, 1603-1613, 2017
222017
Rpl3l gene deletion in mice reduces heart weight over time
KM Grimes, V Prasad, J Huo, Y Kuwabara, D Vanhoutte, TA Baldwin, ...
Frontiers in Physiology 14, 30, 2023
42023
Basic Cardiovascular Sciences Scientific Sessions 2018: Innovating in Cardiovascular Research
JW McNamara, KM Grimes, S Sadayappan
Circulation Research 123 (9), 1024-1029, 2018
32018
Pre-B-cell Leukemia Homeobox Interacting Protein 1 is a Novel Regulator of Growth Signaling in the Heart
KM Grimes, A Pyo, JD Molkentin
Circulation research 125 (Suppl_1), A918-A918, 2019
12019
Cardiac function in an extraordinarily long-lived rodent, the naked mole-rat
KM Grimes, YA Chiao, ML Lindsey, R Buffenstein
Circulation 126 (suppl_21), A9857-A9857, 2012
12012
Exploring MCUb Function in the Heart and Its Role in Ischemia Reperfusion Injury
J Huo, K Grimes, M Sargent, A York, J Kwong, J Molkentin
Circulation Research 125 (Suppl_1), A546-A546, 2019
2019
Identifying Downstream Effectors of the Extracellular Signal-related Kinase 1/2-controlled Directional Growth Response in Cardiomyocytes
KM Grimes, M Maillet, JD Molkentin
Circulation Research 123 (Suppl_1), A306-A306, 2018
2018
MAINTENANCE OF GLUTATHIONE REDOX STATUS IN THE NAKED MOLE-RAT HEART UNDER CONDITIONS OF HIGH OXIDATIVE STRESS
KM Grimes, R Buffenstein
GERONTOLOGIST 55, 163-164, 2015
2015
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