Kevin T. Love
Kevin T. Love
Director of Business Development and Operations, Arsia Therapeutics
Verified email at arsiarx.com
TitleCited byYear
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
H Lee, AKR Lytton-Jean, Y Chen, KT Love, AI Park, ED Karagiannis, ...
Nature nanotechnology 7 (6), 389, 2012
6952012
Lipid-like materials for low-dose, in vivo gene silencing
KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ...
Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010
6712010
Therapeutic siRNA silencing in inflammatory monocytes in mice
F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ...
Nature biotechnology 29 (11), 1005, 2011
5332011
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ...
Nature biotechnology 31 (7), 653, 2013
4092013
Gold, poly (β-amino ester) nanoparticles for small interfering RNA delivery
JS Lee, JJ Green, KT Love, J Sunshine, R Langer, DG Anderson
Nano letters 9 (6), 2402-2406, 2009
2892009
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ...
Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014
2492014
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ...
Journal of the American Chemical Society 134 (16), 6948-6951, 2012
2492012
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ...
Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011
1822011
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
R Haq, S Yokoyama, EB Hawryluk, GB Jönsson, DT Frederick, K McHenry, ...
Proceedings of the National Academy of Sciences 110 (11), 4321-4326, 2013
1702013
Lipidoid-coated iron oxide nanoparticles for efficient DNA and siRNA delivery
S Jiang, AA Eltoukhy, KT Love, R Langer, DG Anderson
Nano letters 13 (3), 1059-1064, 2013
1592013
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis
YH Huang, Y Bao, W Peng, M Goldberg, K Love, DA Bumcrot, G Cole, ...
Proceedings of the National Academy of Sciences 106 (9), 3426-3430, 2009
1332009
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,450,298, 2013
1232013
Systemic RNAi-mediated gene silencing in nonhuman primate and rodent myeloid cells
TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ...
Molecular Therapy-Nucleic Acids 1, e4, 2012
1012012
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
CA Alabi, KT Love, G Sahay, H Yin, KM Luly, R Langer, DG Anderson
Proceedings of the National Academy of Sciences 110 (32), 12881-12886, 2013
862013
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ...
Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012
852012
Aminoalcohol lipidoids and uses thereof
KP Mahon, KT Love, CG Levins, KA Whitehead, RS Langer, DG Anderson
US Patent 8,969,353, 2015
652015
Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery
KP Mahon, KT Love, KA Whitehead, J Qin, A Akinc, E Leshchiner, ...
Bioconjugate chemistry 21 (8), 1448-1454, 2010
652010
FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes
CA Alabi, KT Love, G Sahay, T Stutzman, WT Young, R Langer, ...
ACS nano 6 (7), 6133-6141, 2012
592012
Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof
Y Dong, KT Love, RS Langer, DG Anderson, D Chen, Y Chen, AJ Vegas, ...
US Patent 9,512,073, 2016
562016
Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
F DeRosa, B Guild, S Karve, L Smith, K Love, JR Dorkin, KJ Kauffman, ...
Gene therapy 23 (10), 699, 2016
552016
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