Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation K Wu, NA Yee, S Srinivasan, A Mahmoodi, M Zakharian, JMM Oneto, ... Chemical Science 12 (4), 1259-1271, 2021 | 70 | 2021 |
Extensive transduction and enhanced spread of a modified AAV2 capsid in the non-human primate CNS J Naidoo, LM Stanek, K Ohno, S Trewman, L Samaranch, P Hadaczek, ... Molecular Therapy 26 (10), 2418-2430, 2018 | 61 | 2018 |
SQ3370 Activates Cytotoxic Drug via Click Chemistry at Tumor and Elicits Sustained Responses in Injected and Non‐Injected Lesions S Srinivasan, NA Yee, K Wu, M Zakharian, A Mahmoodi, M Royzen, ... Advanced Therapeutics 4 (3), 2000243, 2021 | 48 | 2021 |
Interactive iBook-based patient education in a neurotrauma clinic R Sahyouni, A Mahmoodi, A Mahmoodi, RR Rajaii, BJ Hasjim, D Bustillo, ... Neurosurgery 81 (5), 787-794, 2017 | 21 | 2017 |
Interactive eBooks in educating patients and their families about head injury regardless of age R Sahyouni, A Mahmoodi, A Mahmoodi, M Huang, DK Tran, JW Chen Clinical neurology and neurosurgery 156, 41-47, 2017 | 16 | 2017 |
SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species S Srinivasan, NA Yee, M Zakharian, M Alečković, A Mahmoodi, ... bioRxiv, 2023.03. 28.534654, 2023 | 6 | 2023 |
The CAPAC Platform maximizes therapeutic benefit and reduces systemic cytotoxic exposure in small and large animals S Srinivasan, NA Yee, A Mahmoodi, M Zakharian, MW Saville, ... Cancer Research 81 (13_Supplement), 1347-1347, 2021 | 1 | 2021 |
82 SQ3370 is a novel approach that decreases adverse drug exposure and achieves robust injected and non-injected anti-tumor responses S Srinivasan, N Yee, K Wu, A Mahmoodi, M Zakharian, M Royzen, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 1* | 2020 |
TD‐P‐011: The Efficacy of Interactive Ibooks in Educating Older Patients on TBI, Concussion, and NPH R Sahyouni, J Chen, A Mahmoodi, A Mahmoodi, D Bustillo, D Tran Alzheimer's & Dementia 12, P156-P156, 2016 | 1 | 2016 |
Click Activated Protodrugs Against Cancer (CAPAC™): A modular platform for tumor directed oncology therapeutics JM McFarland, A Mahmoodi, M Zakharian, S Srinivasan, NA Yee, ... Cancer Research 82 (12_Supplement), 1894-1894, 2022 | | 2022 |
695 Combination of click chemistry-based SQ3370 with immunotherapies enhances antitumor effect in murine tumors with minimized systemic toxicity A Mahmoodi, S Srinivasan, M Zakharian, N Yee, J McFarland, JM Oneto Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
9P Click Activated Protodrugs Against Cancer (CAPAC) platform enhances the safety, pharmacokinetics, and antitumor efficacy of cancer therapies in vivo S Srinivasan, NA Yee, A Mahmoodi, M Zakharian, MW Saville, ... Annals of Oncology 32, S363, 2021 | | 2021 |
SQ3370 enhances the safety and therapeutic index of cytotoxic agents via local activation therapy with improved local and systemic immune response N Yee, S Srinivasan, A Mahmoodi, M Zakharian, M Royzen, JM Oneto Cancer Research 80 (16_Supplement), 6245-6245, 2020 | | 2020 |
Effect of local activation via SQ3370 on the safety of chemotherapy with concomitant anti-tumor immune response. S Srinivasan, NA Yee, A Mahmoodi, M Zakharian, JM Mejia Oneto Journal of Clinical Oncology 38 (15_suppl), e15525-e15525, 2020 | | 2020 |
Axonal transport of a modified AAV2 in the non-human primate brain K Ohno, LM Stanek, J Naidoo, S Trewman, L Samaranch, P Hadaczek, ... HUMAN GENE THERAPY 29 (12), A153-A153, 2018 | | 2018 |
Changing the Face of Modern Medicine: Stem Cell and Gene Therapy Organized Jointly by the European Society of Gene & Cell Therapy (ESGCT), International Society for Stem Cell … KM Champion, P Albertini, I Visigalli, F Cecere, N Carriglio, ... Human Gene Therapy 29 (12), A1-A169, 2018 | | 2018 |
Widespread Transduction and Spread of a Modified AAV2 Capsid in the Non Human Primate Central Nervous System J Naidoo, L Stanek, K Ohno, S Trewman, L Samaranch, P Hadaczek, ... MOLECULAR THERAPY 26 (5), 150-150, 2018 | | 2018 |
Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation. K Wu, NA Yee, S Srinivasan, A Mahmoodi, M Zakharian, JMM Oneto, ... | | |