Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two UK regions OI Kalantzi, FL Martin, GO Thomas, RE Alcock, HR Tang, SC Drury, ... Environmental Health Perspectives 112 (10), 1085-1091, 2004 | 299 | 2004 |
In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: a multi-centre comparison study JJM Van de Sandt, JA Van Burgsteden, S Cage, PL Carmichael, I Dick, ... Regulatory Toxicology and Pharmacology 39 (3), 271-281, 2004 | 278 | 2004 |
Extracting biological information with computational analysis of Fourier-transform infrared (FTIR) biospectroscopy datasets: current practices to future perspectives J Trevisan, PP Angelov, PL Carmichael, AD Scott, FL Martin Analyst 137 (14), 3202-3215, 2012 | 269 | 2012 |
Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways S Bhattacharya, Q Zhang, PL Carmichael, K Boekelheide, ME Andersen PloS one 6 (6), e20887, 2011 | 236 | 2011 |
Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type P Fowler, K Smith, J Young, L Jeffrey, D Kirkland, S Pfuhler, P Carmichael Mutation Research/Genetic Toxicology and Environmental Mutagenesis 742 (1-2 …, 2012 | 226 | 2012 |
Biospectroscopy to metabolically profile biomolecular structure: a multistage approach linking computational analysis with biomarkers JG Kelly, J Trevisan, AD Scott, PL Carmichael, HM Pollock, ... Journal of proteome research 10 (4), 1437-1448, 2011 | 215 | 2011 |
Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack DR Lloyd, DH Phillips, PL Carmichael Chemical research in toxicology 10 (4), 393-400, 1997 | 211 | 1997 |
Comparison of the formation of 8-hydroxy-2 ¡-deoxyguanosine and single-and double-strand breaks in DNA mediated by fenton reactions DR Lloyd, PL Carmichael, DH Phillips Chemical research in toxicology 11 (5), 420-427, 1998 | 185 | 1998 |
Lack of genotoxicity of tamoxifen in human endometrium PL Carmichael, AHN Ugwumadu, P Neven, AJ Hewer, GK Poon, ... Cancer Research 56 (7), 1475-1479, 1996 | 170 | 1996 |
IRootLab: a free and open-source MATLAB toolbox for vibrational biospectroscopy data analysis J Trevisan, PP Angelov, AD Scott, PL Carmichael, FL Martin Bioinformatics 29 (8), 1095-1097, 2013 | 166 | 2013 |
Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment Y Adeleye, M Andersen, R Clewell, M Davies, M Dent, S Edwards, ... Toxicology 332, 102-111, 2015 | 165 | 2015 |
Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen MR Osborne, A Hewer, IR Hardcastle, PL Carmichael, DH Phillips Cancer research 56 (1), 66-71, 1996 | 159 | 1996 |
Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis. J Nair, PL Carmichael, RC Fernando, DH Phillips, AJ Strain, H Bartsch Cancer epidemiology, biomarkers & prevention: a publication of the American …, 1998 | 149 | 1998 |
Analysis of Tamoxifen and Its Metabolites by On-Line Capillary Electrophoresis− Electrospray Ionization Mass Spectrometry Employing Nonaqueous Media Containing Surfactants W Lu, GK Poon, PL Carmichael, RB Cole Analytical chemistry 68 (4), 668-674, 1996 | 148 | 1996 |
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway J Yin, J Guo, Q Zhang, L Cui, L Zhang, T Zhang, J Zhao, J Li, A Middleton, ... Toxicology in vitro 51, 1-10, 2018 | 139 | 2018 |
á-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes DH Phillips, PL Carmichael, A Hewer, KJ Cole, GK Poon Cancer Research 54 (21), 5518-5522, 1994 | 132 | 1994 |
In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results DJ Kirkland, M Aardema, N Banduhn, P Carmichael, R Fautz, JR Meunier, ... Mutagenesis 22 (3), 161-175, 2007 | 121 | 2007 |
Induction of activating mutations in the human c‐Ha‐ras‐1 proto‐oncogene by oxygen free radicals MQ Du, PL Carmichael, DH Phillips Molecular carcinogenesis 11 (3), 170-175, 1994 | 113 | 1994 |
Evaluation of an automated in vitro micronucleus assay in CHO-K1 cells D Diaz, A Scott, P Carmichael, W Shi, C Costales Mutation Research/Genetic Toxicology and Environmental Mutagenesis 630 (1-2 …, 2007 | 112 | 2007 |
t4 workshop report: pathways of toxicity A Kleensang, A Maertens, M Rosenberg, S Fitzpatrick, J Lamb, ... Altex 31 (1), 53, 2014 | 106 | 2014 |