Genomic instability—an evolving hallmark of cancer S Negrini, VG Gorgoulis, TD Halazonetis Nature reviews Molecular cell biology 11 (3), 220-228, 2010 | 2779 | 2010 |
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions VG Gorgoulis, LVF Vassiliou, P Karakaidos, P Zacharatos, A Kotsinas, ... Nature 434 (7035), 907-913, 2005 | 2371 | 2005 |
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints J Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ... Nature 444 (7119), 633-637, 2006 | 2234 | 2006 |
An oncogene-induced DNA damage model for cancer development TD Halazonetis, VG Gorgoulis, J Bartek science 319 (5868), 1352-1355, 2008 | 2069 | 2008 |
Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 1531 | 2019 |
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks Y Huyen, O Zgheib, RA DiTullio Jr, VG Gorgoulis, P Zacharatos, TJ Petty, ... Nature 432 (7015), 406-411, 2004 | 1069 | 2004 |
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer T Cooks, IS Pateras, O Tarcic, H Solomon, AJ Schetter, S Wilder, ... Cancer cell 23 (5), 634-646, 2013 | 479 | 2013 |
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ... Nature communications 9 (1), 771, 2018 | 391 | 2018 |
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer R Di Micco, G Sulli, M Dobreva, M Liontos, OA Botrugno, G Gargiulo, ... Nature cell biology 13 (3), 292-302, 2011 | 367 | 2011 |
Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues EA Georgakopoulou, K Tsimaratou, K Evangelou, MPJ Fernandez, ... Aging (Albany NY) 5 (1), 37, 2013 | 344 | 2013 |
“High risk” HPV types are frequently detected in potentially malignant and malignant oral lesions, but not in normal oral mucosa M Bouda, VG Gorgoulis, NG Kastrinakis, A Giannoudis, E Tsoli, ... Modern Pathology 13 (6), 644-653, 2000 | 326 | 2000 |
Hypomethylation of retrotransposable elements correlates with genomic instability in non‐small cell lung cancer A Daskalos, G Nikolaidis, G Xinarianos, P Savvari, A Cassidy, ... International journal of cancer 124 (1), 81-87, 2009 | 320 | 2009 |
Advances in the biology of oral cancer PK Tsantoulis, NG Kastrinakis, AD Tourvas, G Laskaris, VG Gorgoulis Oral oncology 43 (6), 523-534, 2007 | 320 | 2007 |
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation M Ogrunc, R Di Micco, M Liontos, L Bombardelli, M Mione, M Fumagalli, ... Cell Death & Differentiation 21 (6), 998-1012, 2014 | 307 | 2014 |
Ageing, cellular senescence and neurodegenerative disease M Kritsilis, S V. Rizou, PN Koutsoudaki, K Evangelou, VG Gorgoulis, ... International journal of molecular sciences 19 (10), 2937, 2018 | 300 | 2018 |
Oncogene-induced senescence: the bright and dark side of the response VG Gorgoulis, TD Halazonetis Current opinion in cell biology 22 (6), 816-827, 2010 | 280 | 2010 |
Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress I Andreadou, F Sigala, EK Iliodromitis, M Papaefthimiou, C Sigalas, ... Journal of molecular and cellular cardiology 42 (3), 549-558, 2007 | 280 | 2007 |
Mammalian RAD52 functions in break-induced replication repair of collapsed DNA replication forks SK Sotiriou, I Kamileri, N Lugli, K Evangelou, C Da-Ré, F Huber, ... Molecular cell 64 (6), 1127-1134, 2016 | 275 | 2016 |
Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia K Harvati, C R÷ ding, AM Bosman, FA Karakostis, R GrŘn, C Stringer, ... Nature 571 (7766), 500-504, 2019 | 269 | 2019 |
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 269 | 2016 |