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Stephen Lessnick
Stephen Lessnick
Nationwide Children's Hospital
Verified email at nationwidechildrens.org
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Cited by
Cited by
Year
RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
N Yagoda, M Von Rechenberg, E Zaganjor, AJ Bauer, WS Yang, ...
Nature 447 (7146), 865-869, 2007
13182007
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma, SL Lessnick, WC Hahn, BR Stockwell
Cancer cell 3 (3), 285-296, 2003
12162003
A second Ewing's sarcoma translocation, t (21; 22), fuses the EWS gene to another ETS–family transcription factor, ERG
PHB Sorensen, SL Lessnick, D Lopez-Terrada, XF Liu, TJ Triche, ...
Nature genetics 6 (2), 146-151, 1994
9031994
Ewing sarcoma 11; 22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.
WA May, ML Gishizky, SL Lessnick, LB Lunsford, BC Lewis, O Delattre, ...
Proceedings of the National Academy of Sciences 90 (12), 5752-5756, 1993
6801993
The Ewing¢s Sarcoma EWS/FLI-1 Fusion Gene Encodes a More Potent Transcriptional Activator and is a More Powerful Transforming Gene than FLI-1
WA May, SL Lessnick, BS Braun, M Klemsz, BC Lewis, LB Lunsford, ...
Molecular and cellular biology 13 (12), 7393-7398, 1993
6421993
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
O Gozani, P Karuman, DR Jones, D Ivanov, J Cha, AA Lugovskoy, ...
Cell 114 (1), 99-111, 2003
6332003
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label …
NM Marina, S Smeland, SS Bielack, M Bernstein, G Jovic, MD Krailo, ...
The Lancet Oncology 17 (10), 1396-1408, 2016
4662016
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
S Smeland, SS Bielack, J Whelan, M Bernstein, P Hogendoorn, MD Krailo, ...
European journal of cancer 109, 36-50, 2019
4472019
Expression profiling of EWS/FLI identifies NKX2. 2 as a critical target gene in Ewing's sarcoma
R Smith, LA Owen, DJ Trem, JS Wong, JS Whangbo, TR Golub, ...
Cancer cell 9 (5), 405-416, 2006
4072006
â-Catenin–induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor
HR Widlund, MA Horstmann, ER Price, J Cui, SL Lessnick, M Wu, X He, ...
The Journal of cell biology 158 (6), 1079-1087, 2002
3402002
A conditional mouse model of synovial sarcoma: insights into a myogenic origin
M Haldar, JD Hancock, CM Coffin, SL Lessnick, MR Capecchi
Cancer cell 11 (4), 375-388, 2007
3232007
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
SL Lessnick, CS Dacwag, TR Golub
Cancer cell 1 (4), 393-401, 2002
3212002
Microsatellites as EWS/FLI response elements in Ewing's sarcoma
K Gangwal, S Sankar, PC Hollenhorst, M Kinsey, SC Haroldsen, AA Shah, ...
Proceedings of the National Academy of Sciences 105 (29), 10149-10154, 2008
3162008
Promiscuous partnerships in Ewing's sarcoma
S Sankar, SL Lessnick
Cancer genetics 204 (7), 351-365, 2011
2712011
EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
A Gorthi, JC Romero, E Loranc, L Cao, LA Lawrence, E Goodale, ...
Nature 555 (7696), 387-391, 2018
2662018
Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene
SL Lessnick, BS Braun, CT Denny, WA May
Oncogene 10 (3), 423-432, 1995
2551995
NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma
M Kinsey, R Smith, SL Lessnick
Molecular Cancer Research 4 (11), 851-859, 2006
2432006
Recent advances in the molecular pathogenesis of Ewing's sarcoma
EC Toomey, JD Schiffman, SL Lessnick
Oncogene 29 (32), 4504-4516, 2010
2352010
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis
BS Braun, R Frieden, SL Lessnick, WA May, CT Denny
Molecular and Cellular Biology, 1995
2331995
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers
IJ Davis, JJ Kim, F Ozsolak, HR Widlund, O Rozenblatt-Rosen, ...
Cancer cell 9 (6), 473-484, 2006
2192006
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