Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer KL Cook, A Wärri, DR Soto-Pantoja, PAG Clarke, MI Cruz, A Zwart, ... Clinical Cancer Research 20 (12), 3222-3232, 2014 | 226 | 2014 |
Endoplasmic reticulum stress protein GRP78 modulates lipid metabolism to control drug sensitivity and antitumor immunity in breast cancer KL Cook, DR Soto-Pantoja, PAG Clarke, MI Cruz, A Zwart, A Wärri, ... Cancer research 76 (19), 5657-5670, 2016 | 107 | 2016 |
Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death KL Cook, PAG Clarke, J Parmar, R Hu, JL Schwartz-Roberts, M Abu-Asab, ... The FASEB Journal 28 (9), 3891-3905, 2014 | 91 | 2014 |
Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy KL Cook, DR Soto-Pantoja, M Abu-Asab, PA Clarke, DD Roberts, ... Cell Biosci 4 (1), 16, 2014 | 74 | 2014 |
Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy DDRRC Katherine L Cook1, David R Soto-Pantoja2, Mones Abu-Asab3, Pamela AG ... Cell & Bioscience 4 (16), 9, 2014 | 74* | 2014 |
Targeting GRP78 and antiestrogen resistance in breast cancer KL Cook, PAG Clarke, R Clarke Future medicinal chemistry 5 (9), 1047-1057, 2013 | 38 | 2013 |
Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer JH Parmar, KL Cook, AN Shajahan-Haq, PAG Clarke, I Tavassoly, ... Interface focus 3 (4), 20130012, 2013 | 33 | 2013 |
Heterozygous ATG7 inhibition enhances endocrine therapy responsiveness through regulation of damage associated molecular patterns and priming the immune system in ER+ breast tumors R Clarke, PAG Clarke, A Wärri, KL Cook Cancer Research 76 (14_Supplement), 904-904, 2016 | | 2016 |
INHIBITING AUTOPHAGY AS A STRATEGY TO IMPROVE ANTIESTROGEN RESPONSES IN BREAST CANCER K Cook, A Waerri, D Soto-Pantoja, P Clarke, I Cruz, A Zwart, R Clarke ANTICANCER RESEARCH 34 (10), 5868-5869, 2014 | | 2014 |
Novel role of glucose-regulated protein 78 mediating lipid metabolism through controlling stearoyl-CoA desaturase 1 KL Cook, PAG Clarke, M Axelrod, A Wärri, R Clarke Cancer Research 74 (19 Supplement), 2443-2443, 2014 | | 2014 |
Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1 K Cook, P Clarke, A Warri, R Clarke Cancer & metabolism 2 (1), 1-1, 2014 | | 2014 |
Estrogen receptor-α (ER) integration of unfolded protein response signaling activates autophagy and production of reactive oxygen species to determine ER+ breast cancer cell fate R Clarke, P Clarke, R Hu, M Abu-Asab, AM Warri, KL Cook Breast & Prostate Cancer, SAT-317-SAT-317, 2013 | | 2013 |
Estrogen receptor-α coordinates the unfolded protein response, autophagy, and reactive oxygen species generation to regulate breast cancer survival. PA Clarke, K Cook, R Hu, JL Schwartz, M Abu-Asab, A Warri, R Clarke Cancer Research 73 (8 Supplement), 4046-4046, 2013 | | 2013 |
Knockdown of estrogen receptor-induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation promoting ROS-induced breast cancer cell death KL Cook, PAG Clarke, J Parmar, R Hu, JL Schwartz-Roberts, M Abu-Asab, ... | | |
SAT-317: Estrogen receptor-α (ER) integration of unfolded protein response signaling activates autophagy and production of reactive oxygen species to determine ER+ breast … R Clarke, P Clarke, R Hu, M Abu-Asab, AM Warri, KL Cook | | |