Παρακολούθηση
Jay T. Goodwin
Jay T. Goodwin
Department of Chemistry, Emory University
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα emory.edu
Τίτλος
Παρατίθεται από
Παρατίθεται από
Έτος
Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat
JJ Lu, K Crimin, JT Goodwin, P Crivori, C Orrenius, L Xing, PJ Tandler, ...
Journal of medicinal chemistry 47 (24), 6104-6107, 2004
1942004
Template-directed synthesis: use of a reversible reaction
JT Goodwin, DG Lynn
Journal of the American Chemical Society 114 (23), 9197-9198, 1992
1801992
In silico predictions of blood-brain barrier penetration: considerations to “keep in mind”
JT Goodwin, DE Clark
Journal of Pharmacology and Experimental Therapeutics 315 (2), 477-483, 2005
1442005
Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume
JT Goodwin, RA Conradi, NFH Ho, PS Burton
Journal of medicinal chemistry 44 (22), 3721-3729, 2001
1322001
Predicting drug absorption: how nature made it a difficult problem
PS Burton, JT Goodwin, TJ Vidmar, BM Amore
Journal of Pharmacology and Experimental Therapeutics 303 (3), 889-895, 2002
1212002
Characterization of the Fusarium toxin equisetin: the use of phenylboronates in structure assignment
NJ Phillips, JT Goodwin, A Fraiman, RJ Cole, DG Lynn
Journal of the American Chemical Society 111 (21), 8223-8231, 1989
1061989
Incorporation of alkylthiol chains at C-5 of deoxyuridine
JT Goodwin, GD Glick
Tetrahedron letters 34 (35), 5549-5552, 1993
681993
Design of multi-phase dynamic chemical networks
C Chen, J Tan, MC Hsieh, T Pan, JT Goodwin, AK Mehta, MA Grover, ...
Nature Chemistry 9 (8), 799-804, 2017
612017
Design, Synthesis, and Analysis of Yeast tRNAPhe Analogs Possessing Intra- and Interhelical Disulfide Cross-Links
JT Goodwin, SE Osborne, EJ Scholle, GD Glick
Journal of the American Chemical Society 118 (22), 5207-5215, 1996
601996
Synthesis of a disulfide stabilized RNA hairpin
JT Goodwin, GD Glick
Tetrahedron letters 35 (11), 1647-1650, 1994
531994
Digital and analog chemical evolution
JT Goodwin, AK Mehta, DG Lynn
Accounts of chemical research 45 (12), 2189-2199, 2012
492012
Strategies toward predicting peptide cellular permeability from computed molecular descriptors
JT Goodwin, RA Conradi, PS Burton, B Mao, TJ Vidmar
The Journal of peptide research 53 (4), 355-369, 1999
481999
In vitro permeability of peptidomimetic drugs: The role of polarized efflux pathways as additional barriers to absorption
PS Burton, JT Goodwin, RA Conradi, NFH Ho, AR Hilgers
Advanced drug delivery reviews 23 (1-3), 143-156, 1997
421997
One among millions: The chemical space of nucleic acid-like molecules
HJ Cleaves, C Butch, PB Burger, J Goodwin, M Meringer
Journal of Chemical Information and Modeling 59 (10), 4266-4277, 2019
342019
227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?
HJII Cleaves, M Meringer, J Goodwin
Astrobiology 15 (7), 538-558, 2015
292015
Improved solid-phase synthesis of long oligoribonucleotides: application to tRNAPhe and tRNAGly
JT Goodwin, WA Stanick, GD Glick
The Journal of Organic Chemistry 59 (26), 7941-7943, 1994
221994
Expanding the informational chemistries of life: peptide/RNA networks
O Taran, C Chen, TO Omosun, MC Hsieh, A Rha, JT Goodwin, AK Mehta, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2017
212017
Probing the structure of an RNA tertiary unfolding transition state
EJ Maglott, JT Goodwin, GD Glick
Journal of the American Chemical Society 121 (32), 7461-7462, 1999
211999
Synthesis of a disulfide cross-linked DNA triple helix
JT Goodwin, SE Osborne, PC Swanson, GD Glick
Tetrahedron letters 35 (26), 4527-4530, 1994
211994
Solubility and permeability measurement and applications in drug discovery
PS Burton, JT Goodwin
Combinatorial chemistry & high throughput screening 13 (2), 101-111, 2010
162010
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