| Is the blood–brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data JN Sarkaria, LS Hu, IF Parney, DH Pafundi, DH Brinkmann, NN Laack, ... Neuro-oncology 20 (2), 184-191, 2018 | 555 | 2018 |
| AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectives CS Chaurasia, M Müller, ED Bashaw, E Benfeldt, J Bolinder, R Bullock, ... Pharmaceutical research 24, 1014-1025, 2007 | 422 | 2007 |
| Application of microdialysis in pharmacokinetic studies WF Elmquist, RJ Sawchuk Pharmaceutical research 14, 267-288, 1997 | 392 | 1997 |
| Drug efflux transporters in the CNS H Sun, H Dai, N Shaik, WF Elmquist Advanced drug delivery reviews 55 (1), 83-105, 2003 | 379 | 2003 |
| Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux HQ Dai, P Marbach, M Lemaire, M Hayes, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 304 (3), 1085-1092, 2003 | 338 | 2003 |
| Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain S Agarwal, R Sane, R Oberoi, JR Ohlfest, WF Elmquist Expert reviews in molecular medicine 13, e17, 2011 | 320 | 2011 |
| Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion EV Batrakova, S Li, WF Elmquist, DW Miller, VY Alakhov, AV Kabanov British journal of cancer 85 (12), 1987-1997, 2001 | 289 | 2001 |
| Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up S Agarwal, A MS Hartz, W F Elmquist, B Bauer Current pharmaceutical design 17 (26), 2793-2802, 2011 | 286 | 2011 |
| Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells Y Zhang, H Han, WF Elmquist, DW Miller Brain research 876 (1-2), 148-153, 2000 | 284 | 2000 |
| Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux S Agarwal, R Sane, JL Gallardo, JR Ohlfest, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 334 (1), 147-155, 2010 | 266 | 2010 |
| Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells H Huai-Yun, DT Secrest, KS Mark, D Carney, C Brandquist, WF Elmquist, ... Biochemical and biophysical research communications 243 (3), 816-820, 1998 | 263 | 1998 |
| Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma RK Oberoi, KE Parrish, TT Sio, RK Mittapalli, WF Elmquist, JN Sarkaria Neuro-oncology 18 (1), 27-36, 2015 | 259 | 2015 |
| Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies EV Batrakova, DW Miller, SHU Li, VY Alakhov, AV Kabanov, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 296 (2), 551-557, 2001 | 246 | 2001 |
| P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib Y Chen, S Agarwal, NM Shaik, C Chen, Z Yang, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 330 (3), 956-963, 2009 | 243 | 2009 |
| Radiogenomics to characterize regional genetic heterogeneity in glioblastoma LS Hu, S Ning, JM Eschbacher, LC Baxter, N Gaw, S Ranjbar, J Plasencia, ... Neuro-oncology 19 (1), 128-137, 2017 | 214 | 2017 |
| Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells Y Zhang, JD Schuetz, WF Elmquist, DW Miller Journal of Pharmacology and Experimental Therapeutics 311 (2), 449-455, 2004 | 211 | 2004 |
| Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: findings in an orthotopic rat xenograft model of glioma S Agarwal, P Manchanda, MA Vogelbaum, JR Ohlfest, WF Elmquist Drug Metabolism and Disposition 41 (1), 33-39, 2013 | 195 | 2013 |
| The role of the breast cancer resistance protein (ABCG2) in the distribution of sorafenib to the brain S Agarwal, R Sane, JR Ohlfest, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 336 (1), 223-233, 2011 | 187 | 2011 |
| Mechanisms limiting distribution of the threonine-protein kinase B-RaFV600E inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases RK Mittapalli, S Vaidhyanathan, AZ Dudek, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 344 (3), 655-664, 2013 | 185 | 2013 |
| Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on the brain distribution of a novel BRAF inhibitor: vemurafenib (PLX4032) RK Mittapalli, S Vaidhyanathan, R Sane, WF Elmquist Journal of Pharmacology and Experimental Therapeutics 342 (1), 33-40, 2012 | 175 | 2012 |
