Shangzhong Li
Shangzhong Li
Manager, Bioinformatics, Pfizer
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Cited by
Cited by
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12 (7), 1-7, 2016
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell Systems 3 (5), 434-443. e8, 2016
Rapid neurogenesis through transcriptional activation in human stem cells
V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ...
Molecular systems biology 10 (11), 760, 2014
A systematic evaluation of methods for tailoring genome-scale metabolic models
S Opdam, A Richelle, B Kellman, S Li, DC Zielinski, NE Lewis
Cell systems 4 (3), 318-329. e6, 2017
A reference genome of the Chinese hamster based on a hybrid assembly strategy
O Rupp, ML MacDonald, S Li, H Dhiman, S Polson, S Griep, K Heffner, ...
Biotechnology and bioengineering 115 (8), 2087-2100, 2018
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ...
Scientific reports 7 (1), 1-12, 2017
Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
Whole-genome sequencing of invasion-resistant cells identifies laminin α2 as a host factor for bacterial invasion
XM Van Wijk, S Döhrmann, BM Hallström, S Li, BG Voldborg, BX Meng, ...
MBio 8 (1), 2017
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature communications 11 (1), 1-10, 2020
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference
K Xiong, KF Marquart, KJ la Cour Karottki, S Li, I Shamie, JS Lee, ...
Biotechnology and bioengineering 116 (7), 1813-1819, 2019
Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology
AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis
Current opinion in structural biology 40, 104-111, 2016
Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
GM LaMonte, P Orjuela-Sanchez, J Calla, LT Wang, S Li, J Swann, ...
Nature communications 10 (1), 1-13, 2019
Awakening dormant glycosyltransferases in CHO cells with CRISPRa
KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ...
Biotechnology and bioengineering 117 (2), 593-598, 2020
Proteogenomic annotation of chinese hamsters reveals extensive novel translation events and endogenous retroviral elements
S Li, SW Cha, K Heffner, DB Hizal, MA Bowen, R Chaerkady, RN Cole, ...
Journal of proteome research 18 (6), 2433-2445, 2019
Combating viral contaminants in CHO cells by engineering innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 1-15, 2019
Systematically gap-filling the genome-scale metabolic model of CHO cells
H Fouladiha, SA Marashi, S Li, Z Li, HO Masson, B Vaziri, NE Lewis
Biotechnology Letters 43 (1), 73-87, 2021
Multiple freeze-thaw cycles lead to a loss of consistency in poly (A)-enriched RNA sequencing
BP Kellman, HM Baghdassarian, T Pramparo, I Shamie, V Gazestani, ...
BMC genomics 22 (1), 1-15, 2021
What does your cell really do? Model-based assessment of mammalian cells metabolic functionalities using omics data
A Richelle, BP Kellman, AT Wenzel, AWT Chiang, T Reagan, ...
bioRxiv, 2020
Enhancing Product and Bioprocess Attributes Using Genome‐Scale Models of CHO Metabolism
S Li, A Richelle, NE Lewis
Cell Culture Engineering: Recombinant Protein Production, 73-95, 2019
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