Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs SE Champer, SY Oh, C Liu, Z Wen, AG Clark, PW Messer, J Champer Science Advances 6 (10), eaaz0525, 2020 | 91 | 2020 |
Performance analysis of novel toxin-antidote CRISPR gene drive systems J Champer, IK Kim, SE Champer, AG Clark, PW Messer BMC biology 18, 1-17, 2020 | 67 | 2020 |
Suppression gene drive in continuous space can result in unstable persistence of both drive and wild‐type alleles J Champer, IK Kim, SE Champer, AG Clark, PW Messer Molecular Ecology 30 (4), 1086-1101, 2021 | 66 | 2021 |
Population dynamics of underdominance gene drive systems in continuous space J Champer, J Zhao, SE Champer, J Liu, PW Messer ACS synthetic biology 9 (4), 779-792, 2020 | 48 | 2020 |
Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives J Champer, SE Champer, IK Kim, AG Clark, PW Messer Evolutionary Applications 14 (4), 1052-1069, 2021 | 41 | 2021 |
Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework SE Champer, N Oakes, R Sharma, P García-Díaz, J Champer, PW Messer PLoS computational biology 17 (12), e1009660, 2021 | 25 | 2021 |
Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations AM Langmüller, J Champer, S Lapinska, L Xie, M Metzloff, SE Champer, ... Elife 11, e71809, 2022 | 15 | 2022 |
Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure SE Champer, IK Kim, AG Clark, PW Messer, J Champer Elife 11, e79121, 2022 | 14 | 2022 |
Finding the strongest gene drive: Simulations reveal unexpected performance differences between Anopheles homing suppression drive candidates SE Champer, IK Kim, AG Clark, PW Messer, J Champer bioRxiv, 2022.03. 28.486009, 2022 | 2 | 2022 |
Modeling CRISPR gene drives for suppression of invasive rodents SE Champer, N Oakes, R Sharma, P García-Díaz, J Champer, PW Messer BioRxiv, 2020.11. 05.369942, 2020 | 1 | 2020 |
A framework for identifying fertility gene targets for mammalian pest control AC Clark, R Edison, K Esvelt, S Kamau, L Dutoit, J Champer, ... Molecular Ecology Resources 24 (2), e13901, 2024 | | 2024 |
Resource-explicit interactions in spatial population models SE Champer, B Chae, BC Haller, J Champer, PW Messer bioRxiv, 2024.01. 13.575512, 2024 | | 2024 |
Experimental and computational tests of CRISPR toxin-antidote gene drive strategies J Champer, E Yang, I Kim, YL Lee, SE Champer, AG Clark, PW Messer Entomology 2019, 2019 | | 2019 |