Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy NS Sharma, VK Gupta, VT Garrido, R Hadad, BC Durden, K Kesh, B Giri, ... The Journal of clinical investigation 130 (1), 451-465, 2020 | 153 | 2020 |
Endothelial activation by platelets from sickle cell anemia patients R Proenca-Ferreira, AF Brugnerotto, VT Garrido, VM Dominical, DM Vital, ... PloS one 9 (2), e89012, 2014 | 57 | 2014 |
Combined MEK and STAT3 inhibition uncovers stromal plasticity by enriching for cancer-associated fibroblasts with mesenchymal stem cell-like features to overcome immunotherapy … J Datta, X Dai, A Bianchi, IDC Silva, S Mehra, VT Garrido, P Lamichhane, ... Gastroenterology 163 (6), 1593-1612, 2022 | 55 | 2022 |
Therapy resistance, cancer stem cells and ECM in cancer: the matrix reloaded K Kesh, VK Gupta, B Durden, V Garrido, B Mateo-Victoriano, SP Lavania, ... Cancers 12 (10), 3067, 2020 | 53 | 2020 |
Hypoxia-driven oncometabolite L-2HG maintains stemness-differentiation balance and facilitates immune evasion in pancreatic cancer VK Gupta, NS Sharma, B Durden, VT Garrido, K Kesh, D Edwards, ... Cancer research 81 (15), 4001-4013, 2021 | 47 | 2021 |
Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea FCM Lopes, F Traina, CB Almeida, FC Leonardo, CF Franco-Penteado, ... haematologica 100 (6), 730, 2015 | 40 | 2015 |
Elevated plasma levels and platelet‐associated expression of the pro‐thrombotic and pro‐inflammatory protein, T NFSF14 (LIGHT), in sickle cell disease VT Garrido, R Proença‐Ferreira, VM Dominical, F Traina, MAC Bezerra, ... British journal of haematology 158 (6), 788-797, 2012 | 39 | 2012 |
Neutrophils of Rheumatoid Arthritis Patients on Anti‐TNF‐α Therapy and in Disease Remission Present Reduced Adhesive Functions in Association with Decreased Circulating … VM Dominical, MB Bértolo, CB Almeida, VT Garrido, LI Miguel, FF Costa, ... Scandinavian journal of immunology 73 (4), 309-318, 2011 | 36 | 2011 |
Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients TM Sakamoto, C Lanaro, MC Ozelo, VT Garrido, ST Olalla-Saad, ... Microvascular research 90, 173-179, 2013 | 34 | 2013 |
Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways K Kesh, VT Garrido, A Dosch, B Durden, VK Gupta, NS Sharma, M Lyle, ... Cell death & disease 11 (11), 967, 2020 | 30 | 2020 |
Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer A Bianchi, I De Castro Silva, NU Deshpande, S Singh, S Mehra, ... Cancer discovery 13 (6), 1428-1453, 2023 | 29 | 2023 |
Association of plasma CD40L with acute chest syndrome in sickle cell anemia VT Garrido, L Sonzogni, SN Mtatiro, FF Costa, N Conran, SL Thein Cytokine 97, 104-107, 2017 | 26 | 2017 |
Long non-coding RNA GAS5 acts as proliferation “brakes” in CD133+ cells responsible for tumor recurrence NS Sharma, P Gnamlin, B Durden, VK Gupta, K Kesh, VT Garrido, ... Oncogenesis 8 (12), 68, 2019 | 22 | 2019 |
Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized … I de Castro Silva, A Bianchi, NU Deshpande, P Sharma, S Mehra, ... Elife 11, e78921, 2022 | 15 | 2022 |
Obesity enriches for tumor protective microbial metabolites and treatment refractory cells to confer therapy resistance in PDAC K Kesh, R Mendez, B Mateo-Victoriano, VT Garrido, B Durden, VK Gupta, ... Gut microbes 14 (1), 2096328, 2022 | 12 | 2022 |
Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling S Mehra, S Srinivasan, S Singh, Z Zhou, V Garrido, IDC Silva, TM Totiger, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 323 (4 …, 2022 | 10 | 2022 |
E-cadherin: an enigma in pancreatic diseases VT Garrido, S Banerjee Cellular and molecular gastroenterology and hepatology 9 (1), 191-192, 2020 | 3 | 2020 |
Interactions of sickle red blood cells with neutrophils are stabilized on endothelial cell layers. VM Dominical, DM Vital, VT Garrido, AA Silveira, ST Olalla-Saad, ... Blood Cells, Molecules & Diseases 56 (1), 38-40, 2015 | 3 | 2015 |
Tumor Cell–Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer SP Singh, AR Dosch, S Mehra, I De Castro Silva, A Bianchi, VT Garrido, ... Cancer Research 84 (8), 1320-1332, 2024 | 2 | 2024 |
Remodeling of stromal immune microenvironment by urolithin A improves survival with immune checkpoint blockade in pancreatic cancer S Mehra, VT Garrido, AR Dosch, P Lamichhane, S Srinivasan, SP Singh, ... Cancer research communications 3 (7), 1224-1236, 2023 | 2 | 2023 |