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William Skarnes
William Skarnes
Professor, The Jackson Laboratory
Verified email at jax.org - Homepage
Title
Cited by
Cited by
Year
A conditional knockout resource for the genome-wide study of mouse gene function
WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ...
Nature 474 (7351), 337-342, 2011
17782011
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
T Serafini, SA Colamarino, ED Leonardo, H Wang, R Beddington, ...
Cell 87 (6), 1001-1014, 1996
15171996
An LDL-receptor-related protein mediates Wnt signalling in mice
KI Pinson, J Brennan, S Monkley, BJ Avery, WC Skarnes
Nature 407 (6803), 535-538, 2000
14602000
High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508-514, 2016
10522016
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ...
Nature methods 11 (4), 399-402, 2014
9562014
The knockout mouse project
Nature genetics 36 (9), 921-924, 2004
7582004
Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes
A Gossler, AL Joyner, J Rossant, WC Skarnes
Science 244 (4903), 463-465, 1989
6571989
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
5162013
Functional analysis of secreted and transmembrane proteins critical to mouse development
KJ Mitchell, KI Pinson, OG Kelly, J Brennan, J Zupicich, P Scherz, ...
Nature genetics 28 (3), 241-249, 2001
4712001
Defining brain wiring patterns and mechanisms through gene trapping in mice
PA Leighton, KJ Mitchell, LV Goodrich, X Lu, K Pinson, P Scherz, ...
Nature 410 (6825), 174-179, 2001
4632001
Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections
H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, ...
Neuron 25 (1), 43-56, 2000
4342000
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser, DR Beier, ...
Nature methods 6 (7), 493-495, 2009
4332009
Capturing genes encoding membrane and secreted proteins important for mouse development.
WC Skarnes, JE Moss, SM Hurtley, RS Beddington
Proceedings of the National Academy of Sciences 92 (14), 6592-6596, 1995
4161995
A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.
WC Skarnes, BA Auerbach, AL Joyner
Genes & development 6 (6), 903-918, 1992
3791992
ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
X Gao, P Tate, P Hu, R Tjian, WC Skarnes, Z Wang
Proceedings of the National Academy of Sciences 105 (18), 6656-6661, 2008
3732008
The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice
OG Kelly, KI Pinson, WC Skarnes
Oxford University Press for The Company of Biologists Limited 131 (12), 2803 …, 2004
3582004
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618-624, 2010
3402010
Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016
3252016
The mammalian gene function resource: the International Knockout Mouse Consortium
A Bradley, K Anastassiadis, A Ayadi, JF Battey, C Bell, MC Birling, ...
Mammalian genome 23, 580-586, 2012
3202012
The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
P Tate, W Skarnes, A Bird
Nature genetics 12 (2), 205-208, 1996
3061996
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