Mutation-specific phenotypes in hiPSC-derived cardiomyocytes carrying either myosin-binding protein C or α-tropomyosin mutation for hypertrophic cardiomyopathy M Ojala, C Prajapati, RP Pölönen, K Rajala, M Pekkanen-Mattila, J Rasku, ... Stem cells international 2016, 2016 | 100 | 2016 |
Modeling of LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cells D Shah, L Virtanen, C Prajapati, M Kiamehr, J Gullmets, G West, ... Cells 8 (6), 594, 2019 | 56 | 2019 |
hiPSC-derived cardiomyocyte model of LQT2 syndrome derived from asymptomatic and symptomatic mutation carriers reproduces clinical differences in aggregates but not in single cells D Shah, C Prajapati, K Penttinen, RM Cherian, JT Koivumäki, ... Cells 9 (5), 1153, 2020 | 27 | 2020 |
Electrophysiological evaluation of human induced pluripotent stem cell-derived cardiomyocytes obtained by different methods C Prajapati, M Ojala, H Lappi, K Aalto-Setälä, M Pekkanen-Mattila Stem Cell Research 51, 102176, 2021 | 21 | 2021 |
Divergent effects of adrenaline in human induced pluripotent stem cell-derived cardiomyocytes obtained from hypertrophic cardiomyopathy C Prajapati, M Ojala, K Aalto-Setälä Disease models & mechanisms 11 (2), dmm032896, 2018 | 21 | 2018 |
Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes C Prajapati, RP Pölönen, K Aalto-Setälä Biology open 7 (7), bio035030, 2018 | 19 | 2018 |
Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes J Kuusela, K Larsson, D Shah, C Prajapati, K Aalto-Setälä Biology Open 6 (6), 777-784, 2017 | 18 | 2017 |
Sex differences in heart: from basics to clinics C Prajapati, J Koivumäki, M Pekkanen-Mattila, K Aalto-Setälä European Journal of Medical Research 27 (1), 241, 2022 | 15 | 2022 |
Separation of HCM and LQT cardiac diseases with machine learning of Ca2+ transient profiles H Joutsijoki, K Penttinen, M Juhola, K Aalto-Setälä Methods of Information in Medicine 58 (04/05), 167-178, 2019 | 10 | 2019 |
Fluorescent hiPSC-derived MYH6-mScarlet cardiomyocytes for real-time tracking, imaging, and cardiotoxicity assays R Maria Cherian, C Prajapati, K Penttinen, M Häkli, JT Koivisto, ... Cell Biology and Toxicology 39 (1), 145-163, 2023 | 3 | 2023 |
The junctophilin-2 mutation p.(Thr161Lys) is associated with hypertrophic cardiomyopathy using patient-specific iPS cardiomyocytes and demonstrates prolonged action potential … J Valtonen, C Prajapati, RM Cherian, S Vanninen, M Ojala, K Leivo, ... Biomedicines 11 (6), 1558, 2023 | 2 | 2023 |
HiPSC-derived cardiomyocyte to model Brugada syndrome: both asymptomatic and symptomatic mutation carriers reveal increased arrhythmogenicity K Penttinen, C Prajapati, D Shah, DK Rajan, RM Cherian, H Swan, ... BMC Cardiovascular Disorders 23 (1), 208, 2023 | 2 | 2023 |
Modelling of genetic cardiac diseases C Prajapati, K Aalto-Setälä Visions of Cardiomyocyte-Fundamental Concepts of Heart Life and Disease, 2019 | 1 | 2019 |
Study of Hypertrophic Cardiomyopathy Using Human Induced Pluripotent Stem Cell Derived Cardiomyocytes CK Prajapati Tampere University Press, 2018 | 1 | 2018 |
New SCN5A mutation P1891A causes left ventricular noncompaction and links Nav1. 5 protein-protein interactions to cardiomyocyte proliferation and tissue compaction Q Majid, C Prajapati, X Liu, J Kari-Koskinen, T Karhu, H Ruskoaho, ... Circulation Research, 2024 | | 2024 |
The Junctophilin-2 Mutation p.(Thr161Lys) Is Associated with Hypertrophic Cardiomyopathy Using Patient-Specific iPS Cardiomyocytes and Demonstrates Prolonged Action Potential … J Valtonen, C Prajapati, RM Cherian, S Vanninen, M Ojala, K Leivo, ... | | 2023 |
CRISPR engineered human iPSC cardiac reporter line RM Cherian, MP Mattila, C Prajapati, K Penttinen, KA Setala CARDIOVASCULAR RESEARCH 114, S18-S18, 2018 | | 2018 |