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Kimberly A. Reynolds
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Cited by
Year
Hot spots for allosteric regulation on protein surfaces
KA Reynolds, RN McLaughlin, R Ranganathan
Cell 147 (7), 1564-1575, 2011
3762011
Evolution-based functional decomposition of proteins
O Rivoire, KA Reynolds, R Ranganathan
PLoS computational biology 12 (6), e1004817, 2016
1472016
Analysis of full and partial agonists binding to â2‐adrenergic receptor suggests a role of transmembrane helix V in agonist‐specific conformational changes
V Katritch, KA Reynolds, V Cherezov, MA Hanson, CB Roth, M Yeager, ...
Journal of Molecular Recognition 22 (4), 307-318, 2009
1452009
An evolutionary hotspot defines functional differences between CRYPTOCHROMES
C Rosensweig, KA Reynolds, P Gao, I Laothamatas, Y Shan, ...
Nature communications 9 (1), 1138, 2018
892018
Identifying conformational changes of the â 2 adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators
KA Reynolds, V Katritch, R Abagyan
Journal of computer-aided molecular design 23 (5), 273-288, 2009
732009
Structural and Computational Characterization of the SHV-1 â-Lactamase-â-Lactamase inhibitor protein interface
KA Reynolds, JM Thomson, KD Corbett, CR Bethel, JM Berger, JF Kirsch, ...
Journal of Biological Chemistry 281 (36), 26745-26753, 2006
702006
High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection
YT Tamer, IK Gaszek, H Abdizadeh, TA Batur, KA Reynolds, AR Atilgan, ...
Molecular biology and evolution 36 (7), 1533-1550, 2019
612019
Evolution-based design of proteins
KA Reynolds, WP Russ, M Socolich, R Ranganathan
Methods in enzymology 523, 213-235, 2013
572013
Computational redesign of the SHV-1 â-lactamase/â-lactamase inhibitor protein interface
KA Reynolds, MS Hanes, JM Thomson, AJ Antczak, JM Berger, ...
Journal of molecular biology 382 (5), 1265-1275, 2008
522008
An object‐oriented library for computational protein design
AB Chowdry, KA Reynolds, MS Hanes, M Voorhies, N Pokala, TM Handel
Journal of computational chemistry 28 (14), 2378-2388, 2007
472007
Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme
S Thompson, Y Zhang, C Ingle, KA Reynolds, T Kortemme
Elife 9, e53476, 2020
392020
Cloning and Characterization of the Dictyostelium discoideum cycloartenol synthase cDNA.
SM Godzina, MA Lovato, M M.M, KA Foster, WK Wilson, W Gu, ...
Lipids 36, 249-255, 2000
352000
A two-enzyme adaptive unit within bacterial folate metabolism
AF Schober, AD Mathis, C Ingle, JO Park, L Chen, JD Rabinowitz, I Junier, ...
Cell reports 27 (11), 3359-3370. e7, 2019
282019
Evolution and engineering of allosteric regulation in protein kinases
D Pincus, JP Pandey, ZA Feder, P Creixell, O Resnekov, KA Reynolds
Science signaling 11 (555), 2018
282018
Structurally distributed surface sites tune allosteric regulation
JW McCormick, MAX Russo, S Thompson, A Blevins, KA Reynolds
Elife 10, e68346, 2021
262021
Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily
C Narayanan, D Gagné, KA Reynolds, N Doucet
Scientific reports 7 (1), 3207, 2017
242017
Strategies for Engineering and Rewiring Kinase Regulation
JW McCormick, D Pincus, O Resnekov, KA Reynolds
Trends in biochemical sciences 45 (3), 259-271, 2020
192020
Specificity and cooperativity at â‐lactamase position 104 in TEM‐1/BLIP and SHV‐1/BLIP interactions
MS Hanes, KA Reynolds, C McNamara, P Ghosh, RA Bonomo, JF Kirsch, ...
Proteins: Structure, Function, and Bioinformatics 79 (4), 1267-1276, 2011
182011
An evolution-based strategy for engineering allosteric regulation
D Pincus, O Resnekov, KA Reynolds
Physical biology 14 (2), 025002, 2017
162017
A simplified strategy for titrating gene expression reveals new relationships between genotype, environment, and bacterial growth
AD Mathis, RM Otto, KA Reynolds
Nucleic Acids Research 49 (1), e6-e6, 2021
152021
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Articles 1–20