Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance A Jahangiri, M De Lay, LM Miller, WS Carbonell, YL Hu, K Lu, MW Tom, ... Clinical Cancer Research 19 (7), 1773-1783, 2013 | 224 | 2013 |
Lactate dehydrogenase A silencing in IDH mutant gliomas C Chesnelong, MM Chaumeil, MD Blough, M Al-Najjar, OD Stechishin, ... Neuro-oncology 16 (5), 686-695, 2014 | 194 | 2014 |
Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy CS Ward, HS Venkatesh, MM Chaumeil, AH Brandes, M VanCriekinge, ... Cancer research 70 (4), 1296-1305, 2010 | 183 | 2010 |
Non-invasive in vivo assessment of IDH1 mutational status in glioma MM Chaumeil, PEZ Larson, HAI Yoshihara, OM Danforth, DB Vigneron, ... Nature communications 4 (1), 2429, 2013 | 143 | 2013 |
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism JL Izquierdo-Garcia, P Viswanath, P Eriksson, L Cai, M Radoul, ... Cancer research 75 (15), 2999-3009, 2015 | 134 | 2015 |
Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma MM Chaumeil, T Ozawa, IW Park, K Scott, CD James, SJ Nelson, ... Neuroimage 59 (1), 193-201, 2012 | 122 | 2012 |
Traumatic brain injury in aged mice induces chronic microglia activation, synapse loss, and complement-dependent memory deficits K Krukowski, A Chou, X Feng, B Tiret, MS Paladini, LK Riparip, ... International journal of molecular sciences 19 (12), 3753, 2018 | 107 | 2018 |
Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma HS Venkatesh, MM Chaumeil, CS Ward, DA Haas-Kogan, CD James, ... Neuro-oncology 14 (3), 315-325, 2012 | 99 | 2012 |
Hyperpolarized [1-13C] Glutamate: A Metabolic Imaging Biomarker of IDH1 Mutational Status in Glioma MM Chaumeil, PEZ Larson, SM Woods, L Cai, P Eriksson, AE Robinson, ... Cancer research 74 (16), 4247-4257, 2014 | 94 | 2014 |
Metabolic reprogramming in mutant IDH1 glioma cells JL Izquierdo-Garcia, P Viswanath, P Eriksson, MM Chaumeil, RO Pieper, ... PloS one 10 (2), e0118781, 2015 | 88 | 2015 |
Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model C Guglielmetti, C Najac, A Didonna, A Van der Linden, SM Ronen, ... Proceedings of the National Academy of Sciences 114 (33), E6982-E6991, 2017 | 86 | 2017 |
Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase JL Izquierdo-Garcia, LM Cai, MM Chaumeil, P Eriksson, AE Robinson, ... PloS one 9 (9), e108289, 2014 | 81 | 2014 |
First hyperpolarized [2-13C] pyruvate MR studies of human brain metabolism BT Chung, HY Chen, J Gordon, D Mammoli, R Sriram, AW Autry, ... Journal of Magnetic Resonance 309, 106617, 2019 | 79 | 2019 |
Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells I Park, J Mukherjee, M Ito, MM Chaumeil, LE Jalbert, K Gaensler, ... Cancer research 74 (23), 7115-7124, 2014 | 78 | 2014 |
Hyperpolarized 13C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring MM Chaumeil, M Radoul, C Najac, P Eriksson, P Viswanath, MD Blough, ... NeuroImage: Clinical 12, 180-189, 2016 | 67 | 2016 |
Studies of metabolism using 13C MRS of hyperpolarized probes MM Chaumeil, C Najac, SM Ronen Methods in enzymology 561, 1-71, 2015 | 61 | 2015 |
Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis MM Chaumeil, J Valette, M Guillermier, E Brouillet, F Boumezbeur, ... Proceedings of the National Academy of Sciences 106 (10), 3988-3993, 2009 | 58 | 2009 |
In vivo metabolic imaging of Traumatic Brain Injury C Guglielmetti, A Chou, K Krukowski, C Najac, X Feng, LK Riparip, S Rosi, ... Scientific reports 7 (1), 17525, 2017 | 53 | 2017 |
MR studies of glioblastoma models treated with dual PI3K/mTOR inhibitor and temozolomide: metabolic changes are associated with enhanced survival M Radoul, MM Chaumeil, P Eriksson, AS Wang, JJ Phillips, SM Ronen Molecular cancer therapeutics 15 (5), 1113-1122, 2016 | 51 | 2016 |
Repeated mild head injury leads to wide-ranging deficits in higher-order cognitive functions associated with the prefrontal cortex A Nolan, E Hennessy, K Krukowski, C Guglielmetti, MM Chaumeil, ... Journal of neurotrauma 35 (20), 2425-2434, 2018 | 48 | 2018 |