Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1 VR DeFilippis, D Alvarado, T Sali, S Rothenburg, K Früh Journal of virology 84 (1), 585-598, 2010 | 270 | 2010 |
West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis GR Medigeshi, AM Lancaster, AJ Hirsch, T Briese, WI Lipkin, V DeFilippis, ... Journal of virology 81 (20), 10849-10860, 2007 | 256 | 2007 |
A hypothesis for DNA viruses as the origin of eukaryotic replication proteins LP Villarreal, VR DeFilippis Journal of virology 74 (15), 7079-7084, 2000 | 249 | 2000 |
Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues AJ Hirsch, JL Smith, NN Haese, RM Broeckel, CJ Parkins, C Kreklywich, ... PLoS pathogens 13 (3), e1006219, 2017 | 245 | 2017 |
Cytomegalovirus immune evasion C Powers, V DeFilippis, D Malouli, K Früh Human cytomegalovirus, 333-359, 2008 | 237 | 2008 |
The window of taxonomic resolution for phylogenies based on mitochondrial cytochrome b WS Moore, VR DeFilippis Avian molecular evolution and systematics, 83-119, 1997 | 200 | 1997 |
Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology AJ Hirsch, VHJ Roberts, PL Grigsby, N Haese, MC Schabel, X Wang, ... Nature communications 9 (1), 263, 2018 | 190 | 2018 |
Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff LK White, T Sali, D Alvarado, E Gatti, P Pierre, D Streblow, VR DeFilippis Journal of virology 85 (1), 606-620, 2011 | 156 | 2011 |
IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin S Botto, DN Streblow, V DeFilippis, L White, CN Kreklywich, PP Smith, ... Blood, The Journal of the American Society of Hematology 117 (1), 352-361, 2011 | 127 | 2011 |
Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity I Messaoudi, J Vomaske, T Totonchy, CN Kreklywich, K Haberthur, ... PLoS neglected tropical diseases 7 (7), e2343, 2013 | 123 | 2013 |
Acute and persistent viral life strategies and their relationship to emerging diseases LP Villarreal, VR Defilippis, KA Gottlieb Virology 272 (1), 1-6, 2000 | 111 | 2000 |
Human cytomegalovirus miR-UL112-3p targets TLR2 and modulates the TLR2/IRAK1/NFκB signaling pathway I Landais, C Pelton, D Streblow, V DeFilippis, S McWeeney, JA Nelson PLoS pathogens 11 (5), e1004881, 2015 | 109 | 2015 |
Characterization of a novel human-specific STING agonist that elicits antiviral activity against emerging alphaviruses TM Sali, KM Pryke, J Abraham, A Liu, I Archer, R Broeckel, JA Staverosky, ... PLoS pathogens 11 (12), e1005324, 2015 | 108 | 2015 |
Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells SC McAllister, SG Hansen, RA Ruhl, CM Raggo, VR DeFilippis, ... Blood 103 (9), 3465-3473, 2004 | 104 | 2004 |
The Src family kinase c-Yes is required for maturation of West Nile virus particles AJ Hirsch, GR Medigeshi, HL Meyers, V DeFilippis, K Früh, T Briese, ... Journal of virology 79 (18), 11943-11951, 2005 | 102 | 2005 |
Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression V Wahl-Jensen, S Kurz, F Feldmann, LK Buehler, J Kindrachuk, ... PLoS neglected tropical diseases 5 (10), e1359, 2011 | 98 | 2011 |
Sequence-specific modifications enhance the broad-spectrum antiviral response activated by RIG-I agonists C Chiang, V Beljanski, K Yin, D Olagnier, F Ben Yebdri, C Steel, ... Journal of virology 89 (15), 8011-8025, 2015 | 97 | 2015 |
Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection VR DeFilippis, B Robinson, TM Keck, SG Hansen, JA Nelson, KJ Früh Journal of virology 80 (2), 1032-1037, 2006 | 95 | 2006 |
The tiers and dimensions of evasion of the type I interferon response by human cytomegalovirus L Amsler, MC Verweij, VR DeFilippis Journal of molecular biology 425 (24), 4857-4871, 2013 | 82 | 2013 |
Viral hijacking of the host ubiquitin system to evade interferon responses K Viswanathan, K Früh, V DeFilippis Current opinion in microbiology 13 (4), 517-523, 2010 | 81 | 2010 |