In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism N Lara-Castillo, NA Kim-Weroha, MA Kamel, B Javaheri, DL Ellies, ... Bone 76, 58-66, 2015 | 151 | 2015 |
Deletion of a single β‐catenin allele in osteocytes abolishes the bone anabolic response to loading B Javaheri, AR Stern, N Lara, M Dallas, H Zhao, Y Liu, LF Bonewald, ... Journal of Bone and Mineral Research 29 (3), 705-715, 2014 | 128 | 2014 |
Spatial relationship between bone formation and mechanical stimulus within cortical bone: combining 3D fluorochrome mapping and poroelastic finite element modelling A Carriero, AF Pereira, AJ Wilson, S Castagno, B Javaheri, AA Pitsillides, ... Bone Reports 8, 72-80, 2018 | 124* | 2018 |
Predicting cortical bone adaptation to axial loading in the mouse tibia AF Pereira, B Javaheri, AA Pitsillides, SJ Shefelbine Journal of the Royal Society Interface 12 (110), 20150590, 2015 | 106 | 2015 |
The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading A Moustafa, T Sugiyama, LK Saxon, G Zaman, A Sunters, VJ Armstrong, ... Bone 44 (5), 930-935, 2009 | 95 | 2009 |
Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling DC Berwick, B Javaheri, A Wetzel, M Hopkinson, J Nixon-Abell, S Grannò, ... Molecular neurodegeneration 12, 1-17, 2017 | 71 | 2017 |
In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography K Madi, KA Staines, BK Bay, B Javaheri, H Geng, AJ Bodey, S Cartmell, ... Nature biomedical engineering 4 (3), 343-354, 2020 | 65 | 2020 |
Aging and mechanoadaptive responsiveness of bone B Javaheri, AA Pitsillides Current osteoporosis reports 17, 560-569, 2019 | 47 | 2019 |
Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation KA Staines, B Javaheri, P Hohenstein, R Fleming, E Ikpegbu, E Unger, ... Journal of Cellular Physiology 232 (11), 3006-3019, 2017 | 44 | 2017 |
Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing B Javaheri, A Carriero, KA Staines, YM Chang, DA Houston, KJ Oldknow, ... Bone 81, 277-291, 2015 | 42 | 2015 |
Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth … G Zaman, A Sunters, GL Galea, B Javaheri, LK Saxon, A Moustafa, ... Journal of Biological Chemistry 287 (6), 3946-3962, 2012 | 41 | 2012 |
Preclinical models for in vitro mechanical loading of bone-derived cells RM Delaine-Smith, B Javaheri, JH Edwards, M Vazquez, RMH Rumney BoneKEy reports 4, 2015 | 38 | 2015 |
Lasting organ-level bone mechanoadaptation is unrelated to local strain B Javaheri, H Razi, S Gohin, S Wylie, YM Chang, P Salmon, PD Lee, ... Science Advances 6 (10), eaax8301, 2020 | 36 | 2020 |
Propagation phase-contrast micro-computed tomography allows laboratory-based three-dimensional imaging of articular cartilage down to the cellular level JN Clark, A Garbout, SA Ferreira, B Javaheri, AA Pitsillides, SM Rankin, ... Osteoarthritis and cartilage 28 (1), 102-111, 2020 | 35 | 2020 |
Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis L Ramos-Mucci, B Javaheri, R van ‘t Hof, G Bou-Gharios, AA Pitsillides, ... Arthritis research & therapy 22, 1-12, 2020 | 33 | 2020 |
Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength SV Lim, M Marenzana, M Hopkinson, EO List, JJ Kopchick, M Pereira, ... Endocrinology 156 (4), 1362-1371, 2015 | 31 | 2015 |
Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis B Javaheri, B Poulet, AJ Al-Jazzar, R de Souza, M Piles, M Hopkinson, ... Bone 103, 308-317, 2017 | 27 | 2017 |
Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response B Javaheri, A Carriero, M Wood, R De Souza, PD Lee, S Shefelbine, ... Scientific reports 8 (1), 6636, 2018 | 25 | 2018 |
A distinctive patchy osteomalacia characterises Phospho1‐deficient mice A Boyde, KA Staines, B Javaheri, JL Millan, AA Pitsillides, C Farquharson Journal of anatomy 231 (2), 298-308, 2017 | 25 | 2017 |
Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo B Javaheri, M Hopkinson, B Poulet, AS Pollard, SJ Shefelbine, YM Chang, ... PloS one 11 (8), e0159657, 2016 | 25 | 2016 |