Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 939 | 2017 |
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems P Mohanraju, KS Makarova, B Zetsche, F Zhang, EV Koonin, ... Science 353 (6299), aad5147, 2016 | 712 | 2016 |
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome VJ Carrión, J Perez-Jaramillo, V Cordovez, V Tracanna, M De Hollander, ... Science 366 (6465), 606-612, 2019 | 681 | 2019 |
Characterizing a thermostable Cas9 for bacterial genome editing and silencing I Mougiakos, P Mohanraju, EF Bosma, V Vrouwe, M Finger Bou, ... Nature communications 8 (1), 1647, 2017 | 145 | 2017 |
CRISPR–Cas ribonucleoprotein mediated homology-directed repair for efficient targeted genome editing in microalgae Nannochloropsis oceanica IMET1 MIS Naduthodi, P Mohanraju, C Südfeld, S D’Adamo, MJ Barbosa, ... Biotechnology for biofuels 12, 1-11, 2019 | 82 | 2019 |
Keeping crispr in check: diverse mechanisms of phage-encoded anti-crisprs D Trasanidou, AS Geros, P Mohanraju, AC Nieuwenweg, FL Nobrega, ... FEMS microbiology letters 366 (9), fnz098, 2019 | 82 | 2019 |
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a SCA Creutzburg, WY Wu, P Mohanraju, T Swartjes, F Alkan, J Gorodkin, ... Nucleic acids research 48 (6), 3228-3243, 2020 | 72 | 2020 |
Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR–Cas effector complexes M Vlot, J Houkes, SJA Lochs, DC Swarts, P Zheng, T Kunne, P Mohanraju, ... Nucleic acids research 46 (2), 873-885, 2018 | 66 | 2018 |
Alternative functions of CRISPR–Cas systems in the evolutionary arms race P Mohanraju, C Saha, P van Baarlen, R Louwen, RHJ Staals, ... Nature Reviews Microbiology 20 (6), 351-364, 2022 | 48 | 2022 |
Prime editing: advances and therapeutic applications Z Zhao, P Shang, P Mohanraju, N Geijsen Trends in Biotechnology 41 (8), 1000-1012, 2023 | 41 | 2023 |
Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA C Saha, P Mohanraju, A Stubbs, G Dugar, Y Hoogstrate, GJ Kremers, ... Science advances 6 (25), eaaz4849, 2020 | 39 | 2020 |
The miniature CRISPR-Cas12m effector binds DNA to block transcription WY Wu, P Mohanraju, C Liao, B Adiego-Pérez, SCA Creutzburg, ... Molecular Cell 82 (23), 4487-4502. e7, 2022 | 32 | 2022 |
Heterologous expression and purification of the CRISPR-Cas12a/Cpf1 protein P Mohanraju, J Van Der Oost, M Jinek, DC Swarts Bio-protocol 8 (9), e2842-e2842, 2018 | 31 | 2018 |
Development of a Cas12a-based genome editing tool for moderate thermophiles P Mohanraju, I Mougiakos, J Albers, M Mabuchi, RT Fuchs, JL Curcuru, ... The CRISPR Journal 4 (1), 82-91, 2021 | 9 | 2021 |
Thermostable Cas9 nucleases J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju US Patent 11,326,162, 2022 | 3 | 2022 |
Thermostable cas9 nucleases J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju US Patent App. 16/469,691, 2019 | 1 | 2019 |
Thermostable CAS9 nucleases J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju US Patent 11,939,605, 2024 | | 2024 |
Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli D Trasanidou, A Potocnik, P Barendse, P Mohanraju, E Bouzetos, ... Communications Biology 6 (1), 1042, 2023 | | 2023 |
Crispr type v-u1 system from mycobacterium mucogenicum and uses thereof J Van Der Oost, P Mohanraju, WY Wu, S Creutzburg US Patent App. 17/624,439, 2022 | | 2022 |
Thermostable cas9 nucleases J Van Der Oost, R Van Kranenburg, EF Bosma, I Mougiakos, P Mohanraju US Patent App. 16/469,683, 2019 | | 2019 |