SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase W Tadros, AL Goldman, T Babak, F Menzies, L Vardy, T Orr-Weaver, ... Developmental cell 12 (1), 143-155, 2007 | 378 | 2007 |
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery M Bezzi, SX Teo, J Muller, WC Mok, SK Sahu, LA Vardy, ZQ Bonday, ... Genes & development 27 (17), 1903-1916, 2013 | 330 | 2013 |
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells J Carlevaro-Fita, A Rahim, R Guigó, LA Vardy, R Johnson Rna 22 (6), 867-882, 2016 | 259 | 2016 |
Lamin B1 fluctuations have differential effects on cellular proliferation and senescence O Dreesen, A Chojnowski, PF Ong, TY Zhao, JE Common, D Lunny, ... Journal of Cell Biology 200 (5), 605-617, 2013 | 253 | 2013 |
PCBP1 suppresses the translation of metastasis-associated PRL-3 phosphatase H Wang, LA Vardy, CP Tan, JM Loo, K Guo, J Li, SG Lim, J Zhou, ... Cancer Cell 18 (1), 52-62, 2010 | 236 | 2010 |
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors S Brown, A Teo, S Pauklin, N Hannan, CHH Cho, B Lim, L Vardy, ... Stem cells 29 (8), 1176-1185, 2011 | 219 | 2011 |
5-Methylcytosine RNA methylation in Arabidopsis thaliana X Cui, Z Liang, L Shen, Q Zhang, S Bao, Y Geng, B Zhang, V Leo, ... Molecular plant 10 (11), 1387-1399, 2017 | 203 | 2017 |
Fission yeast ch‐TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2‐dependent spindle checkpoint MA Garcia, L Vardy, N Koonrugsa, T Toda The EMBO journal, 2001 | 179 | 2001 |
The fission yeast γ-tubulin complex is required in G1 phase and is a component of the spindle assembly checkpoint L Vardy, T Toda The EMBO journal 19 (22), 6098-6111, 2000 | 157 | 2000 |
Identification of novel temperature-sensitive lethal alleles in essential β-tubulin and nonessential α2-tubulin genes as fission yeast polarity mutants P Radcliffe, D Hirata, D Childs, L Vardy, T Toda Molecular biology of the cell 9 (7), 1757-1771, 1998 | 106 | 1998 |
Determination of isoform-specific RNA structure with nanopore long reads JGA Aw, SW Lim, JX Wang, FRP Lambert, WT Tan, Y Shen, Y Zhang, ... Nature biotechnology 39 (3), 336-346, 2021 | 101 | 2021 |
Transcriptional consequences of genomic structural aberrations in breast cancer K Inaki, AM Hillmer, L Ukil, F Yao, XY Woo, LA Vardy, KFB Zawack, ... Genome research 21 (5), 676-687, 2011 | 101 | 2011 |
Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation M Sato, L Vardy, M Angel Garcia, N Koonrugsa, T Toda Molecular biology of the cell 15 (4), 1609-1622, 2004 | 95 | 2004 |
Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast PA Radcliffe, D Hirata, L Vardy, T Toda Molecular biology of the cell 10 (9), 2987-3001, 1999 | 88 | 1999 |
Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress A Giannakakis, J Zhang, P Jenjaroenpun, S Nama, N Zainolabidin, ... Scientific reports 5 (1), 9737, 2015 | 84 | 2015 |
The Drosophila PNG kinase complex regulates the translation of cyclin B L Vardy, TL Orr-Weaver Developmental cell 12 (1), 157-166, 2007 | 83 | 2007 |
Regulating translation of maternal messages: multiple repression mechanisms L Vardy, TL Orr-Weaver Trends in cell biology 17 (11), 547-554, 2007 | 81 | 2007 |
A fourth component of the fission yeast γ-tubulin complex, Alp16, is required for cytoplasmic microtubule integrity and becomes indispensable when γ-tubulin function is compromised A Fujita, L Vardy, MA Garcia, T Toda Molecular biology of the cell 13 (7), 2360-2373, 2002 | 81 | 2002 |
RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors QWL Wong, J Li, SR Ng, SG Lim, H Yang, LA Vardy RNA biology 11 (1), 33-41, 2014 | 70 | 2014 |
A conserved small GTP-binding protein Alp41 is essential for the cofactor-dependent biogenesis of microtubules in fission yeast PA Radcliffe, L Vardy, T Toda FEBS letters 468 (1), 84-88, 2000 | 70 | 2000 |