Unveiling the non-repair face of the Base Excision Repair pathway in RNA processing: A missing link between DNA repair and gene expression? G Antoniali, MC Malfatti, G Tell DNA repair 56, 65-74, 2017 | 70 | 2017 |
Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti‐tumor properties M Poletto, MC Malfatti, D Dorjsuren, PL Scognamiglio, D Marasco, ... Molecular carcinogenesis 55 (5), 688-704, 2016 | 66 | 2016 |
Platinum salts in patients with breast cancer: a focus on predictive factors M Garutti, G Pelizzari, M Bartoletti, MC Malfatti, L Gerratana, G Tell, ... International Journal of Molecular Sciences 20 (14), 3390, 2019 | 62 | 2019 |
Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2 MC Malfatti, S Balachander, G Antoniali, KD Koh, C Saint-Pierre, ... Nucleic acids research 45 (19), 11193-11212, 2017 | 54 | 2017 |
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence S Burra, D Marasco, MC Malfatti, G Antoniali, A Virgilio, V Esposito, ... DNA repair 73, 129-143, 2019 | 50 | 2019 |
Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway M Codrich, M Comelli, MC Malfatti, C Mio, D Ayyildiz, C Zhang, MR Kelley, ... DNA repair 82, 102675, 2019 | 34 | 2019 |
Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN M Codrich, E Dalla, C Mio, G Antoniali, MC Malfatti, S Marzinotto, ... Journal of Experimental & Clinical Cancer Research 40, 1-17, 2021 | 32 | 2021 |
APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC MC Malfatti, L Gerratana, E Dalla, M Isola, G Damante, C Di Loreto, ... Journal of Experimental & Clinical Cancer Research 38, 1-23, 2019 | 31 | 2019 |
Coping with RNA damage with a focus on APE1, a BER enzyme at the crossroad between DNA damage repair and RNA processing/decay MC Malfatti, G Antoniali, M Codrich, G Tell DNA repair 104, 103133, 2021 | 26 | 2021 |
New perspectives in cancer biology from a study of canonical and non-canonical functions of base excision repair proteins with a focus on early steps MC Malfatti, G Antoniali, M Codrich, S Burra, G Mangiapane, E Dalla, ... Mutagenesis 35 (1), 129-149, 2020 | 24 | 2020 |
Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes G Mangiapane, I Parolini, K Conte, MC Malfatti, J Corsi, M Sanchez, ... Journal of Biological Chemistry 296, 2021 | 21 | 2021 |
Unlike the Escherichia coli counterpart, archaeal RNase HII cannot process ribose monophosphate abasic sites and oxidized ribonucleotides embedded in DNA MC Malfatti, G Henneke, S Balachander, KD Koh, G Newnam, R Uehara, ... Journal of Biological Chemistry 294 (35), 13061-13072, 2019 | 16 | 2019 |
Revisiting two decades of Research focused on Targeting APE1 for Cancer Therapy: the pros and cons MC Malfatti, A Bellina, G Antoniali, G Tell Cells 12 (14), 1895, 2023 | 7 | 2023 |
Role of condensates in modulating DNA repair pathways and its implication for chemoresistance G Dall˘Agnese, A Dall˘Agnese, SF Banani, M Codrich, MC Malfatti, ... Journal of Biological Chemistry 299 (6), 2023 | 7 | 2023 |
Combining deep phenotyping of serum proteomics and clinical data via machine learning for COVID-19 biomarker discovery AP Beltrami, M De Martino, E Dalla, MC Malfatti, F Caponnetto, M Codrich, ... International Journal of Molecular Sciences 23 (16), 9161, 2022 | 7 | 2022 |
APE1 interacts with the nuclear exosome complex protein MTR4 and is involved in cisplatin‐and 5‐fluorouracil‐induced RNA damage response M Codrich, M Degrassi, MC Malfatti, G Antoniali, A Gorassini, D Ayyildiz, ... The FEBS Journal 290 (7), 1740-1764, 2023 | 4 | 2023 |
AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity MC Malfatti, M Codrich, E Dalla, C D'Ambrosio, F Storici, A Scaloni, G Tell Antioxidants & Redox Signaling 39 (7-9), 411-431, 2023 | 3 | 2023 |
Emerging concepts on the early steps of base excision repair pathway with a focus on gene expression G Antoniali, MC Malfatti, G Tell | 3 | 2020 |
The Apurinic/Apyrimidinic Endodeoxyribonuclease 1 is an RNA G-quadruplex binding protein and regulates miR-92b expression in cancer cells A Bellina, MC Malfatti, G Salgado, AM Fleming, G Antoniali, N Gualandi, ... bioRxiv, 2024.02. 22.581538, 2024 | | 2024 |
In Vitro Assay to Measure APE1 Enzymatic Activity on Ribose Monophosphate Abasic Site MC Malfatti, G Antoniali, G Tell Base Excision Repair Pathway: Methods and Protocols, 21-38, 2023 | | 2023 |