Παρακολούθηση
Mathias Cobbaut
Mathias Cobbaut
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα crick.ac.uk
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Παρατίθεται από
Παρατίθεται από
Έτος
Equivocal, explicit and emergent actions of PKC isoforms in cancer
PJ Parker, SJ Brown, V Calleja, P Chakravarty, M Cobbaut, M Linch, ...
Nature Reviews Cancer 21 (1), 51-63, 2021
452021
Dysfunctional mechanotransduction through the YAP/TAZ/Hippo pathway as a feature of chronic disease
M Cobbaut, S Karagil, L Bruno, MDC Diaz de la Loza, FE Mackenzie, ...
Cells 9 (1), 151, 2020
442020
Function and regulation of protein kinase D in oxidative stress: a tale of isoforms
M Cobbaut, J Van Lint
Oxidative Medicine and Cellular Longevity 2018, 2018
342018
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
D Bauters, M Cobbaut, L Geys, J Van Lint, B Hemmeryckx, HR Lijnen
Molecular metabolism 6 (7), 715-724, 2017
302017
Protein kinase D2: a versatile player in cancer biology
N Azoitei, M Cobbaut, A Becher, J Van Lint, T Seufferlein
Oncogene 37 (10), 1263-1278, 2018
242018
Design, synthesis and biological evaluation of pyrazolo [3, 4-d] pyrimidine-based protein kinase D inhibitors
P Gilles, RS Kashyap, MJ Freitas, S Ceusters, K Van Asch, A Janssens, ...
European Journal of Medicinal Chemistry 205, 112638, 2020
172020
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+ 1 loop
M Cobbaut, R Derua, H Döppler, HJ Lou, S Vandoninck, P Storz, BE Turk, ...
Scientific reports 7 (1), 887, 2017
172017
Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo [3, 4-d] pyrimidine analogues
K Verschueren, M Cobbaut, J Demaerel, L Saadah, ARD Voet, J Van Lint, ...
MedChemComm 8 (3), 640-646, 2017
142017
The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity
A Elbediwy, Y Zhang, M Cobbaut, P Riou, RS Tan, SK Roberts, C Tynan, ...
Journal of Cell Science 132 (8), jcs223743, 2019
132019
Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation
M Cobbaut, R Derua, PJ Parker, E Waelkens, V Janssens, J Van Lint
FEBS letters 592 (14), 2432-2443, 2018
92018
Control of atypical PKCι membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface
M Cobbaut, NQ McDonald, PJ Parker
Journal of Biological Chemistry 299 (7), 2023
32023
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells
N Lockwood, S Martini, A Lopez-Pardo, K Deiss, HA Segeren, RK Semple, ...
Cancer research 82 (9), 1762-1773, 2022
22022
Into the fold: advances in understanding aPKC membrane dynamics
M Cobbaut, PJ Parker, NQ McDonald
Biochemical Journal 480 (24), 2037-2044, 2023
2023
A distinctive requirement for p53 in the genome protective Topoisomerase 2a-dependent G2 arrest in hTERT positive cancer cells
N Lockwood, S Martini, A López-Pardo, K Deiss, HA Segeren, RK Semple, ...
Cancer Research, 2022
2022
First person–Mathias Cobbaut and Ahmed Elbediwy
M Cobbaut, A Elbediwy
Journal of Cell Science 132 (8), jcs231928, 2019
2019
Design, Synthesis and Evaluation of Protein Kinase D Inhibitors
P Gilles, K Verschueren, M Cobbaut, J Demaerel, J Van Lint, A Voet, ...
Merck Organic Chemistry Symposium, Date: 2017/12/07-2017/12/08, Location …, 2017
2017
Abstract B08: Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment
M Cobbaut, R Derua, E Waelkens, P Störz, V Janssens, JV Lint
Cancer Research 77 (22_Supplement), B08-B08, 2017
2017
Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment
M Cobbaut, R Derua, E Waelkens, P Storz, V Janssens, J Van Lint
CANCER RESEARCH 77 (22), 2017
2017
Nieuwe inzichten in de farmacologische inhibitie en isovormspecifieke regulatie van Proteine Kinase D2
M Cobbaut
2017
Identification of a zyxin family based network of novel Protein Kinase D interactors via BioID
J Van Lint, R Derua, L Saadah, E Waelkens, V Janssens, M Cobbaut
Novo Nordisk Copenhagen Bioscience Conference on Protein Signaling-from …, 2016
2016
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