Essential role of the ESX-5 secretion system in outer membrane permeability of pathogenic mycobacteria LS Ates, R Ummels, S Commandeur, R van der Weerd, M Sparrius, ... PLoS genetics 11 (5), e1005190, 2015 | 172 | 2015 |
Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis LS Ates, A Dippenaar, R Ummels, SR Piersma, AD van der Woude, ... Nature microbiology 3 (2), 181-188, 2018 | 113 | 2018 |
Type VII secretion: a highly versatile secretion system LS Ates, ENG Houben, W Bitter Virulence mechanisms of bacterial pathogens, 357-384, 2016 | 110* | 2016 |
The ESX-5 system of pathogenic mycobacteria is involved in capsule integrity and virulence through its substrate PPE10 LS Ates, AD van der Woude, J Bestebroer, G van Stempvoort, ... PLoS pathogens 12 (6), e1005696, 2016 | 79 | 2016 |
New insights into the mycobacterial PE and PPE proteins provide a framework for future research LS Ates Molecular microbiology 113 (1), 4-21, 2020 | 75 | 2020 |
D iscovery of the type VII ESX‐1 secretion needle? LS Ates, R Brosch Molecular microbiology 103 (1), 7-12, 2017 | 41 | 2017 |
Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity LS Ates, A Dippenaar, F Sayes, A Pawlik, C Bouchier, L Ma, RM Warren, ... Genome biology and evolution 10 (8), 1858-1874, 2018 | 39 | 2018 |
RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection LS Ates, F Sayes, W Frigui, R Ummels, MPM Damen, D Bottai, MA Behr, ... PLoS pathogens 14 (6), e1007139, 2018 | 39 | 2018 |
Multiplexed quantitation of intraphagocyte Mycobacterium tuberculosis secreted protein effectors F Sayes, C Blanc, LS Ates, N Deboosere, M Orgeur, F Le Chevalier, ... Cell Reports 23 (4), 1072-1084, 2018 | 39 | 2018 |
Comparison of in vitro activities of tigecycline, doxycycline, and tetracycline against the spirochete Borrelia burgdorferi L Ates, C Hanssen-Hübner, DE Norris, D Richter, P Kraiczy, KP Hunfeld Ticks and Tick-borne Diseases 1 (1), 30-34, 2010 | 32 | 2010 |
Separate signaling events control TCR downregulation and T cell activation in primary human T cells LEH van der Donk, LS Ates, J van der Spek, LM Tukker, TBH Geijtenbeek, ... Immunity, Inflammation and Disease 9 (1), 223-238, 2021 | 14 | 2021 |
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts M Orgeur, W Frigui, A Pawlik, S Clark, A Williams, LS Ates, L Ma, ... Microbial Genomics 7 (2), 000505, 2021 | 14 | 2021 |
Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier MJ Burggraaf, LS Ates, A Speer, K Van Der Kuij, C Kuijl, W Bitter Microbial cell factories 18, 1-14, 2019 | 12 | 2019 |
Multiplexed quantitation of intraphagocyte Mycobacterium tuberculosis secreted protein effectors. Cell Rep. 23, 1072–1084 F Sayes, C Blanc, LS Ates, N Deboosere, M Orgeur, F Le Chevalier, ... | 7 | 2018 |
Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells L Waanders, LEH van der Donk, LS Ates, J Maaskant, JL van Hamme, ... Journal for Immunotherapy of Cancer 11 (4), 2023 | 2 | 2023 |
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes LEH van der Donk, J van der Spek, T van Duivenvoorde, MS Ten Brink, ... Biology open 11 (2), bio059032, 2022 | 1 | 2022 |
A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis SJ Pidot, S Klatt, LS Ates, W Frigui, F Sayes, L Majlessi, H Izumi, IR Monk, ... bioRxiv, 2024.01. 23.576949, 2024 | | 2024 |
PPE's and the ESX-5 secretion system: Shining light on the dark matter of mycobacteria LS Ates | | 2016 |