| Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming … K Horiuchi, N Amizuka, S Takeshita, H Takamatsu, M Katsuura, H Ozawa, ... Journal of bone and mineral research 14 (7), 1239-1249, 1999 | 1131 | 1999 |
| Dysbiosis and Staphylococcus aureus colonization drives inflammation in atopic dermatitis T Kobayashi, M Glatz, K Horiuchi, H Kawasaki, H Akiyama, DH Kaplan, ... Immunity 42 (4), 756-766, 2015 | 557 | 2015 |
| Cutting edge: TNF-α-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock K Horiuchi, T Kimura, T Miyamoto, H Takaishi, Y Okada, Y Toyama, ... The Journal of Immunology 179 (5), 2686-2689, 2007 | 377 | 2007 |
| Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx K Horiuchi, S Le Gall, M Schulte, T Yamaguchi, K Reiss, G Murphy, ... Molecular biology of the cell 18 (1), 176-188, 2007 | 364 | 2007 |
| ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor α, L-selectin, and tumor … SM Le Gall, P Bobé, K Reiss, K Horiuchi, XD Niu, D Lundell, DR Gibb, ... Molecular biology of the cell 20 (6), 1785-1794, 2009 | 349 | 2009 |
| Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin K Nagao, T Kobayashi, K Moro, M Ohyama, T Adachi, DY Kitashima, ... Nature immunology 13 (8), 744-752, 2012 | 326 | 2012 |
| Potential role for ADAM15 in pathological neovascularization in mice K Horiuchi, G Weskamp, L Lum, HP Hammes, H Cai, TA Brodie, T Ludwig, ... Molecular and cellular biology 23 (16), 5614-5624, 2003 | 221 | 2003 |
| Activity-dependent proteolytic cleavage of neuroligin-1 K Suzuki, Y Hayashi, S Nakahara, H Kumazaki, J Prox, K Horiuchi, ... Neuron 76 (2), 410-422, 2012 | 218 | 2012 |
| Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration S Suzuki, N Fujita, N Hosogane, K Watanabe, K Ishii, Y Toyama, ... Arthritis research & therapy 17, 1-17, 2015 | 202 | 2015 |
| Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins β1 and β2 K Horiuchi, HM Zhou, K Kelly, K Manova, CP Blobel Developmental biology 283 (2), 459-471, 2005 | 200 | 2005 |
| VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling S Swendeman, K Mendelson, G Weskamp, K Horiuchi, U Deutsch, ... Circulation research 103 (9), 916-918, 2008 | 194 | 2008 |
| iRHOM2 is a critical pathogenic mediator of inflammatory arthritis PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ... The Journal of clinical investigation 123 (2), 928-932, 2013 | 193 | 2013 |
| Homeostatic control of sebaceous glands by innate lymphoid cells regulates commensal bacteria equilibrium T Kobayashi, B Voisin, EA Kennedy, JH Jo, HY Shih, A Truong, T Doebel, ... Cell 176 (5), 982-997. e16, 2019 | 185 | 2019 |
| Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation CW Franzke, C Cobzaru, A Triantafyllopoulou, S Löffek, K Horiuchi, ... Journal of Experimental Medicine 209 (6), 1105-1119, 2012 | 181 | 2012 |
| Essential role for ADAM19 in cardiovascular morphogenesis HM Zhou, G Weskamp, V Chesneau, U Sahin, A Vortkamp, K Horiuchi, ... Molecular and cellular biology 24 (1), 96-104, 2004 | 168 | 2004 |
| TACE (ADAM17) inhibits Schwann cell myelination R La Marca, F Cerri, K Horiuchi, A Bachi, ML Feltri, L Wrabetz, CP Blobel, ... Nature neuroscience 14 (7), 857-865, 2011 | 162 | 2011 |
| Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes G Weskamp, K Mendelson, S Swendeman, S Le Gall, Y Ma, S Lyman, ... Circulation research 106 (5), 932-940, 2010 | 158 | 2010 |
| Metalloprotease‐disintegrin ADAM8: expression analysis and targeted deletion in mice K Kelly, G Hutchinson, D Nebenius‐Oosthuizen, AJH Smith, JW Bartsch, ... Developmental dynamics: an official publication of the American Association …, 2005 | 143 | 2005 |
| The IRE1α–XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix T Tohmonda, Y Miyauchi, R Ghosh, M Yoda, S Uchikawa, J Takito, ... EMBO reports 12 (5), 451-457, 2011 | 133 | 2011 |
| Lung endothelial ADAM17 regulates the acute inflammatory response to lipopolysaccharide D Dreymueller, C Martin, T Kogel, J Pruessmeyer, FM Hess, K Horiuchi, ... EMBO molecular medicine 4 (5), 412-423, 2012 | 123 | 2012 |
