Georgios Drakakis
Georgios Drakakis
Post Doctoral Research Associate
Verified email at - Homepage
Cited by
Cited by
Target prediction utilising negative bioactivity data covering large chemical space
LH Mervin, AM Afzal, G Drakakis, R Lewis, O Engkvist, A Bender
Journal of cheminformatics 7 (1), 1-16, 2015
Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
AC Ravindranath, N Perualila-Tan, A Kasim, G Drakakis, S Liggi, ...
Molecular BioSystems 11 (1), 86-96, 2015
Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts
S Liggi, G Drakakis, A Koutsoukas, I Cortes-Ciriano, P Martínez-Alonso, ...
Future Medicinal Chemistry 6 (18), 2029-2056, 2014
Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts
S Liggi, G Drakakis, AE Hendry, KM Hanson, SC Brewerton, GN Wheeler, ...
Molecular Informatics 32 (11‐12), 1009-1024, 2013
Jaqpot Quattro: A Novel Computational Web Platform for Modeling and Analysis in Nanoinformatics
C Chomenidis, G Drakakis, G Tsiliki, E Anagnostopoulou, A Valsamis, ...
Journal of Chemical Information and Modeling 57 (9), 2161-2172, 2017
Diversity Selection of Compounds Based on ‘Protein Affinity Fingerprints’ Improves Sampling of Bioactive Chemical Space
HP Nguyen, A Koutsoukas, F Mohd Fauzi, G Drakakis, M Maciejewski, ...
Chemical biology & drug design 82 (3), 252-266, 2013
Global mapping of traditional chinese medicine into bioactivity space and pathways annotation improves mechanistic understanding and discovers relationships between therapeutic …
M Zobir, S Zuraidah, F Mohd Fauzi, S Liggi, G Drakakis, X Fu, TP Fan, ...
Evidence-Based Complementary and Alternative Medicine 2016, 2016
Polypharmacological in Silico Bioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat
G Drakakis, KA Wafford, SC Brewerton, MJ Bodkin, DA Evans, A Bender
ACS chemical biology 12 (6), 1593-1602, 2017
Comparing Global and Local Likelihood Score Thresholds in Multiclass Laplacian-Modified Naďve Bayes Protein Target Prediction
G Drakakis, A Koutsoukas, S C Brewerton, M J Bodkin, D A Evans, ...
Combinatorial chemistry & high throughput screening 18 (3), 323-330, 2015
Decision Trees for Continuous Data and Conditional Mutual Information as a Criterion for Splitting Instances
G Drakakis, S Moledina, C Chomenidis, P Doganis, H Sarimveis
Combinatorial chemistry & high throughput screening 19 (5), 423-428, 2016
Using machine learning techniques for rationalising phenotypic readouts from a rat sleeping model
G Drakakis, A Koutsoukas, SC Brewerton, D Evans, A Bender
Journal of Cheminformatics 5 (1), 1-1, 2013
Comparative mode-of-action analysis following manual and automated phenotype detection in Xenopus laevis
G Drakakis, AE Hendry, K Hanson, SC Brewerton, MJ Bodkin, DA Evans, ...
MedChemComm 5 (3), 386-396, 2014
Elucidating Compound Mechanism of Action and Predicting Cytotoxicity Using Machine Learning Approaches, Taking Prediction Confidence into Account
G Drakakis, I Cortés‐Ciriano, B Alexander‐Dann, A Bender
Current protocols in chemical biology 11 (3), e73, 2019
Answering Scientific Questions with linked European Nanosafety Data.
EL Willighagen, M Rautenberg, D Gebele, L Rieswijk, F Ehrhart, J Chang, ...
SWAT4LS, 2016
eNanoMapper–A database and ontology framework for design and safety assessment of nanomaterials
G Kilic, B Fadeel, L Farcal, H Sarimveis, P Doganis, G Drakakis, G Tsiliki, ...
Toxicology Letters, S118-S119, 2016
Drug repurposing candidates against COVID-19
G Drakakis, C Chomenidis, G Tsiliki, A Dokoumetzidis
https://zenodo. org/api/files/850dc565-5ddb-4328-a25c-04bc36300b05/PPF …, 2020
Computational Modelling of Biological Responses to Engineered Nanomaterials
P Doganis, G Tsiliki, G Drakakis, C Chomenidis, P Nymark, P Kohonen, ...
Nanotoxicology, 276-303, 2017
Biclustering Methods in Chemoinformatics and Molecular Modelling in Drug Discovery Experiments: Connecting Gene Expression and Target Prediction Data
NJ Perualila, Z Shkedy, AC Ravindranath, G Drakakis, S Liggi, A Bender, ...
Applied Biclustering Methods for Big and High-Dimensional Data Using R, 175-192, 2016
Research Article Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships …
SZM Zobir, FM Fauzi, S Liggi, G Drakakis, X Fu, TP Fan, A Bender
Relating GPCRs pharmacological space based on ligands chemical similarities
A Koutsoukas, R Torella, G Drakakis, A Bender, RC Glen
Journal of cheminformatics 5 (1), 1-1, 2013
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