| Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration CA Lindemans, M Calafiore, AM Mertelsmann, MH O’connor, JA Dudakov, ... Nature 528 (7583), 560-564, 2015 | 982 | 2015 |
| CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 225 | 2020 |
| The intestinal stem cell niche: homeostasis and adaptations AJM Santos, YH Lo, AT Mah, CJ Kuo Trends in cell biology 28 (12), 1062-1078, 2018 | 203 | 2018 |
| An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 153 | 2021 |
| Applications of organoids for cancer biology and precision medicine YH Lo, K Karlsson, CJ Kuo Nature Cancer 1 (8), 761-773, 2020 | 106 | 2020 |
| Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth H Zhao, YH Lo, L Ma, SE Waltz, JK Gray, MC Hung, SC Wang Molecular cancer therapeutics 10 (1), 29-36, 2011 | 105 | 2011 |
| T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage S Takashima, ML Martin, SA Jansen, Y Fu, J Bos, D Chandra, ... Science Immunology 4 (42), eaay8556, 2019 | 104 | 2019 |
| A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and nonessential modes of oncogenic transformation YH Lo, KS Kolahi, Y Du, CY Chang, A Krokhotin, A Nair, WD Sobba, ... Cancer Discovery 11 (6), 1562-1581, 2021 | 91 | 2021 |
| Transcriptional regulation by ATOH1 and its target SPDEF in the intestine YH Lo, E Chung, Z Li, YW Wan, MM Mahe, MS Chen, TK Noah, KN Bell, ... Cellular and Molecular Gastroenterology and Hepatology 3 (1), 51-71, 2017 | 78 | 2017 |
| Sox4 promotes Atoh1-independent intestinal secretory differentiation toward tuft and enteroendocrine fates AD Gracz, LA Samsa, MJ Fordham, DC Trotier, B Zwarycz, YH Lo, K Bao, ... Gastroenterology 155 (5), 1508-1523. e10, 2018 | 75 | 2018 |
| Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration S Gilbert, H Nivarthi, CN Mayhew, YH Lo, TK Noah, J Vallance, T Rülicke, ... Stem cell reports 4 (2), 209-225, 2015 | 71 | 2015 |
| Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer H Zhao, PC Ho, YH Lo, A Espejo, MT Bedford, MC Hung, SC Wang PLoS One 7 (1), e29416, 2012 | 68 | 2012 |
| SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity TK Noah, YH Lo, A Price, G Chen, E King, MK Washington, BJ Aronow, ... Gastroenterology 144 (5), 1012-1023. e6, 2013 | 66 | 2013 |
| The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer H Zhao, MS Chen, YH Lo, SE Waltz, J Wang, PC Ho, J Vasiliauskas, ... Oncogene 33 (11), 1429-1437, 2014 | 63 | 2014 |
| Epithelial WNT ligands are essential drivers of intestinal stem cell activation WY Zou, SE Blutt, XL Zeng, MS Chen, YH Lo, D Castillo-Azofeifa, ... Cell reports 22 (4), 1003-1015, 2018 | 60 | 2018 |
| SPDEF induces quiescence of colorectal cancer cells by changing the transcriptional targets of β-catenin YH Lo, TK Noah, MS Chen, W Zou, E Borras, E Vilar, NF Shroyer Gastroenterology 153 (1), 205-218. e8, 2017 | 45 | 2017 |
| Growth Factor–Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer MS Chen, YH Lo, X Chen, CS Williams, JM Donnelly, ZK Criss, S Patel, ... Molecular Cancer Research 17 (3), 697-708, 2019 | 36 | 2019 |
| The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1 D Almohazey, YH Lo, CV Vossler, AJ Simmons, JJ Hsieh, EB Bucar, ... Cell Death & Differentiation 24 (5), 855-865, 2017 | 36 | 2017 |
| Epidermal growth factor receptor protects proliferating cell nuclear antigen from cullin 4A protein-mediated proteolysis YH Lo, PC Ho, SC Wang Journal of Biological Chemistry 287 (32), 27148-27157, 2012 | 32 | 2012 |
| Deterministic evolution and stringent selection during preneoplasia CC Kasper Karlsson, Moritz J Przybilla, Eran Kotler, Aziz Khan, Hang Xu ... Nature 618 (7964), 383-393, 2023 | 31* | 2023 |
Noah Freeman ShroyerBaylor College of MedicineVerified email at bcm.edu
