Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase LA Tintignac, J Lagirand, S Batonnet, V Sirri, MP Leibovitch, ... Journal of Biological Chemistry 280 (4), 2847-2856, 2005 | 514 | 2005 |
Protein kinase B/Akt at a glance E Fayard, LA Tintignac, A Baudry, BA Hemmings Journal of cell science 118 (24), 5675-5678, 2005 | 452 | 2005 |
Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting LA Tintignac, HR Brenner, MA Rüegg Physiological reviews 95 (3), 809-852, 2015 | 388 | 2015 |
The initiation factor eIF3‐f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy J Lagirand‐Cantaloube, N Offner, A Csibi, MP Leibovitch, ... The EMBO journal 27 (8), 1266-1276, 2008 | 373 | 2008 |
PKB and the mitochondria: AKTing on apoptosis A Parcellier, LA Tintignac, E Zhuravleva, BA Hemmings Cellular signalling 20 (1), 21-30, 2008 | 291 | 2008 |
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy P Castets, S Lin, N Rion, S Di Fulvio, K Romanino, M Guridi, S Frank, ... Cell metabolism 17 (5), 731-744, 2013 | 273 | 2013 |
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope M Castedo, T Roumier, J Blanco, KF Ferri, J Barretina, LA Tintignac, ... The EMBO journal 21 (15), 4070-4080, 2002 | 185 | 2002 |
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy CF Bentzinger, S Lin, K Romanino, P Castets, M Guridi, S Summermatter, ... Skeletal muscle 3, 1-16, 2013 | 160 | 2013 |
The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse A Csibi, K Cornille, MP Leibovitch, A Poupon, LA Tintignac, AMJ Sanchez, ... PloS one 5 (2), e8994, 2010 | 143 | 2010 |
MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines A Csibi, MP Leibovitch, K Cornille, LA Tintignac, SA Leibovitch Journal of biological chemistry 284 (7), 4413-4421, 2009 | 129 | 2009 |
Stabilization of MyoD by direct binding to p57Kip2 EG Reynaud, MP Leibovitch, LAJ Tintignac, K Pelpel, M Guillier, ... Journal of Biological Chemistry 275 (25), 18767-18776, 2000 | 125 | 2000 |
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia DJ Ham, A Börsch, S Lin, M Thürkauf, M Weihrauch, JR Reinhard, ... Nature communications 11 (1), 4510, 2020 | 117 | 2020 |
Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21 M Guridi, LA Tintignac, S Lin, B Kupr, P Castets, MA Rüegg Science signaling 8 (402), ra113-ra113, 2015 | 102 | 2015 |
Cyclin E–Cdk2 Phosphorylation Promotes Late G1-Phase Degradation of MyoD in Muscle Cells LA Tintignac, MP Leibovitch, M Kitzmann, A Fernandez, B Ducommun, ... Experimental cell research 259 (1), 300-307, 2000 | 78 | 2000 |
Myostatin inactivation increases myotube size through regulation of translational initiation machinery J Rodriguez, B Vernus, M Toubiana, E Jublanc, L Tintignac, S Leibovitch, ... Journal of cellular biochemistry 112 (12), 3531-3542, 2011 | 57 | 2011 |
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis L Mazelin, B Panthu, AS Nicot, E Belotti, L Tintignac, G Teixeira, Q Zhang, ... Journal of molecular and cellular cardiology 97, 213-225, 2016 | 55 | 2016 |
Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry LAJ Tintignac, V Sirri, MP Leibovitch, Y Lécluse, M Castedo, D Metivier, ... Molecular and cellular biology 24 (4), 1809-1821, 2004 | 52 | 2004 |
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia A Börsch, DJ Ham, N Mittal, LA Tintignac, E Migliavacca, JN Feige, ... Communications Biology 4 (1), 194, 2021 | 48 | 2021 |
Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism M Guridi, B Kupr, K Romanino, S Lin, D Falcetta, L Tintignac, MA Rüegg Skeletal muscle 6, 1-14, 2016 | 48 | 2016 |
SIRT3, a Mitochondrial NAD+-Dependent Deacetylase, Is Involved in the Regulation of Myoblast Differentiation W Abdel Khalek, F Cortade, V Ollendorff, L Lapasset, L Tintignac, B Chabi, ... PLoS One 9 (12), e114388, 2014 | 44 | 2014 |