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Michael Closser
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Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity
EO Mazzoni, S Mahony, M Closser, CA Morrison, S Nedelec, DJ Williams, ...
Nature neuroscience 16 (9), 1219-1227, 2013
2352013
Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution
W Leung, CD Shaffer, LK Reed, ST Smith, W Barshop, W Dirkes, ...
G3: Genes, Genomes, Genetics 5 (5), 719-740, 2015
1062015
Embryonic stem cell–based mapping of developmental transcriptional programs
EO Mazzoni, S Mahony, M Iacovino, CA Morrison, G Mountoufaris, ...
Nature methods 8 (12), 1056-1058, 2011
872011
Expression of terminal effector genes in mammalian neurons is maintained by a dynamic relay of transient enhancers
HS Rhee, M Closser, Y Guo, EV Bashkirova, GC Tan, DK Gifford, ...
Neuron 92 (6), 1252-1265, 2016
802016
An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity
M Closser, Y Guo, P Wang, T Patel, S Jang, J Hammelman, JC De Nooij, ...
Neuron 110 (1), 70-85. e6, 2022
252022
Ranking reprogramming factors for cell differentiation
J Hammelman, T Patel, M Closser, H Wichterle, D Gifford
Nature methods 19 (7), 812-822, 2022
152022
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
T Patel, J Hammelman, S Aziz, S Jang, M Closser, TL Michaels, JA Blum, ...
Nature communications 13 (1), 5427, 2022
102022
High resolution discovery of chromatin interactions
Y Guo, K Krismer, M Closser, H Wichterle, DK Gifford
Nucleic acids research 47 (6), e35-e35, 2019
102019
Long 3′ UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation
TJ Dorrity, H Shin, KA Wiegand, J Aruda, M Closser, E Jung, JA Gertie, ...
Science Immunology 8 (88), eadg2979, 2023
92023
General and cell-type-specific aspects of the motor neuron maturation transcriptional program
T Patel, J Hammelman, M Closser, DK Gifford, H Wichterle
BioRxiv, 2021.03. 05.434185, 2021
82021
High resolution mapping of enhancer-promoter interactions
C Reeder, M Closser, HM Poh, K Sandhu, H Wichterle, D Gifford
Plos one 10 (5), e0122420, 2015
72015
Regulatory logic of cellular diversity in the nervous system
ME Closser
Columbia University, 2018
2018
Stem Cells As a Tool for Studying the Developmental Regulation of Gene Expression
H Wichterle, M Closser, EO Mazzoni, S Mahony, Y Guo
SHORT COURSE I, 17, 0
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Articles 1–13