Distinct interactions of PML-RARα and PLZF-RARα with co-repressors determine differential responses to RA in APL LZ He, F Guidez, C Tribioli, D Peruzzi, M Ruthardt, A Zelent, PP Pandolfi Nature genetics 18 (2), 126-135, 1998 | 729 | 1998 |
Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML-and PLZF-RARα underlie molecular pathogenesis and treatment of acute promyelocytic leukemia F Guidez, S Ivins, J Zhu, M Söderström, S Waxman, A Zelent Blood, The Journal of the American Society of Hematology 91 (8), 2634-2642, 1998 | 387 | 1998 |
Translocations of the RARα gene in acute promyelocytic leukemia A Zelent, F Guidez, A Melnick, S Waxman, JD Licht Oncogene 20 (49), 7186-7203, 2001 | 288 | 2001 |
Resistance to all-trans retinoic acid (ATRA) therapy in relapsing acute promyelocytic leukemia: study of in vitro ATRA sensitivity and cellular retinoic acid binding protein … L Delva, M Cornic, N Balitrand, F Guidez, JM Miclea, A Delmer, F Teillet, ... | 240 | 1993 |
PLZF-RAR alpha fusion proteins generated from the variant t (11; 17)(q23; q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild … Z Chen, F Guidez, P Rousselot, A Agadir, SJ Chen, ZY Wang, L Degos, ... Proceedings of the National Academy of Sciences 91 (3), 1178-1182, 1994 | 217 | 1994 |
Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein. S Dong, J Zhu, A Reid, P Strutt, F Guidez, HJ Zhong, ZY Wang, J Licht, ... Proceedings of the National Academy of Sciences 93 (8), 3624-3629, 1996 | 211 | 1996 |
Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein F Guidez, K Petrie, AM Ford, H Lu, CA Bennett, A MacGregor, ... Blood, The Journal of the American Society of Hematology 96 (7), 2557-2561, 2000 | 195 | 2000 |
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network A Caye, M Strullu, F Guidez, B Cassinat, S Gazal, O Fenneteau, E Lainey, ... Nature genetics 47 (11), 1334-1340, 2015 | 191 | 2015 |
The histone deacetylase 9 gene encodes multiple protein isoforms K Petrie, F Guidez, L Howell, L Healy, S Waxman, M Greaves, A Zelent Journal of Biological Chemistry 278 (18), 16059-16072, 2003 | 182 | 2003 |
Rexinoid-Triggered Differentiation and Tumor-Selective Apoptosis of Acute Myeloid Leukemia by Protein Kinase A–Mediated Desubordination of Retinoid X Receptor L Altucci, A Rossin, O Hirsch, A Nebbioso, D Vitoux, E Wilhelm, F Guidez, ... Cancer Research 65 (19), 8754-8765, 2005 | 132 | 2005 |
Poor response to all-trans retinoic acid therapy in at (11; 17) PLZF/RAR alpha patient. F Guidez, W Huang, JH Tong, C Dubois, N Balitrand, S Waxman, ... Leukemia 8 (2), 312-317, 1994 | 129 | 1994 |
Induction of retinoic acid-binding protein in normal and malignant human myeloid cells by retinoic acid in acute promyelocytic leukemia patients M Cornic, L Delva, F Guidez, N Balitrand, L Degos, C Chomienne Cancer research 52 (12), 3329-3334, 1992 | 126 | 1992 |
Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein F Guidez, L Howell, M Isalan, M Cebrat, RM Alani, S Ivins, I Hormaeche, ... Molecular and cellular biology 25 (13), 5552-5566, 2005 | 116 | 2005 |
The PML-RAR alpha gene product of the t (15; 17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells. P Rousselot, B Hardas, A Patel, F Guidez, J Gäken, S Castaigne, ... Oncogene 9 (2), 545-551, 1994 | 116 | 1994 |
HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements M Mielcarek, D Zielonka, A Carnemolla, JT Marcinkowski, F Guidez Frontiers in cellular neuroscience 9, 42, 2015 | 109 | 2015 |
Hematopoietic growth factor expression and ATRA sensitivity in acute promyelocytic blast cells C Dubois, MH Schlageter, A de Gentile, F Guidez, N Balitrand, ... Blood 83 (11), 3264-3270, 1994 | 100 | 1994 |
Acute promyelocytic leukemia: a paradigm for differentiation therapy D Grimwade, AR Mistry, E Solomon, F Guidez Acute Myelogenous Leukemia: Genetics, Biology and Therapy, 219-235, 2010 | 93 | 2010 |
RARα-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia F Guidez, S Parks, H Wong, JV Jovanovic, A Mays, AF Gilkes, KI Mills, ... Proceedings of the National Academy of Sciences 104 (47), 18694-18699, 2007 | 80 | 2007 |
Synthesis and evaluation of a potent and selective cell-permeable p300 histone acetyltransferase inhibitor Y Zheng, K Balasubramanyam, M Cebrat, D Buck, F Guidez, A Zelent, ... Journal of the American Chemical Society 127 (49), 17182-17183, 2005 | 79 | 2005 |
The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU. 1 and c-Jun AC Li, FRB Guidez, JG Collier, CK Glass Journal of Biological Chemistry 273 (9), 5389-5399, 1998 | 77 | 1998 |