| Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin CN Toepfer, H Wakimoto, AC Garfinkel, B McDonough, D Liao, J Jiang, ... Science translational medicine 11 (476), eaat1199, 2019 | 171 | 2019 |
| The role of super-relaxed myosin in skeletal and cardiac muscle JW McNamara, A Li, CG Dos Remedios, R Cooke Biophysical reviews 7, 5-14, 2015 | 138 | 2015 |
| Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes JW McNamara, A Li, NJ Smith, S Lal, RM Graham, KB Kooiker, ... Journal of molecular and cellular cardiology 94, 65-71, 2016 | 130 | 2016 |
| MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy JW McNamara, A Li, S Lal, JM Bos, SP Harris, J Van Der Velden, ... PloS one 12 (6), e0180064, 2017 | 121 | 2017 |
| Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin JW McNamara, RR Singh, S Sadayappan Proceedings of the National Academy of Sciences 116 (24), 11731-11736, 2019 | 91 | 2019 |
| Hypertrophic cardiomyopathy clinical phenotype is independent of gene mutation and mutation dosage SK Viswanathan, HK Sanders, JW McNamara, A Jagadeesan, A Jahangir, ... PloS one 12 (11), e0187948, 2017 | 68 | 2017 |
| Cardiomyocyte SMAD4-dependent TGF-β signaling is essential to maintain adult heart homeostasis P Umbarkar, AP Singh, M Gupte, VK Verma, CL Galindo, Y Guo, Q Zhang, ... JACC: Basic to Translational Science 4 (1), 41-53, 2019 | 47 | 2019 |
| Skeletal myosin binding protein-C: An increasingly important regulator of striated muscle physiology JW McNamara, S Sadayappan Archives of biochemistry and biophysics 660, 121-128, 2018 | 47 | 2018 |
| Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies Z Ge, A Li, J McNamara, C Dos Remedios, S Lal Heart failure reviews 24, 743-758, 2019 | 46 | 2019 |
| The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease CG Dos Remedios, SP Lal, A Li, J McNamara, A Keogh, PS Macdonald, ... Biophysical Reviews 9, 431-441, 2017 | 40 | 2017 |
| The N terminus of myosin-binding protein C extends toward actin filaments in intact cardiac muscle S Rahmanseresht, KH Lee, TS O’Leary, JW McNamara, S Sadayappan, ... Journal of General Physiology 153 (3), e202012726, 2021 | 35 | 2021 |
| Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems A Li, SR Nelson, S Rahmanseresht, F Braet, AS Cornachione, SB Previs, ... Proceedings of the National Academy of Sciences 116 (43), 21882-21892, 2019 | 32 | 2019 |
| Probenecid improves cardiac function in patients with heart failure with reduced ejection fraction in vivo and cardiomyocyte calcium sensitivity in vitro N Robbins, M Gilbert, M Kumar, JW McNamara, P Daly, SE Koch, ... Journal of the American Heart Association 7 (2), e007148, 2018 | 30 | 2018 |
| Supporting the heart: Functions of the cardiomyocyte's non-sarcomeric cytoskeleton KM Grimes, V Prasad, JW McNamara Journal of molecular and cellular cardiology 131, 187-196, 2019 | 29 | 2019 |
| Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function R Blazev, CS Carl, YK Ng, J Molendijk, CT Voldstedlund, Y Zhao, D Xiao, ... Cell Metabolism 34 (10), 1561-1577. e9, 2022 | 27 | 2022 |
| Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury DY Barefield, JW McNamara, TL Lynch, DWD Kuster, S Govindan, L Haar, ... Journal of molecular and cellular cardiology 129, 236-246, 2019 | 27 | 2019 |
| Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction T Song, JW McNamara, W Ma, M Landim-Vieira, KH Lee, LA Martin, ... Proceedings of the National Academy of Sciences 118 (17), e2003596118, 2021 | 22 | 2021 |
| The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent KM Grimes, DY Barefield, M Kumar, JW McNamara, ST Weintraub, ... Pflügers Archiv-European Journal of Physiology 469, 1603-1613, 2017 | 22 | 2017 |
| Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility TL Lynch IV, M Kumar, JW McNamara, DWD Kuster, M Sivaguru, ... Journal of molecular and cellular cardiology 156, 33-44, 2021 | 17 | 2021 |
| A novel homozygous intronic variant in TNNT2 associates with feline cardiomyopathy JW McNamara, M Schuckman, RC Becker, S Sadayappan Frontiers in Physiology 11, 608473, 2020 | 16 | 2020 |
Sakthivel SadayappanProfessor of Internal Medicine at University of CincinnatiVerified email at ucmail.uc.edu
