Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo A Burleigh, A Chanalaris, MD Gardiner, C Driscoll, O Boruc, J Saklatvala, ... Arthritis & Rheumatism 64 (7), 2278-2288, 2012 | 123 | 2012 |
ADAMTS and ADAM metalloproteinases in osteoarthritis–looking beyond the ‘usual suspects’ CY Yang, A Chanalaris, L Troeberg Osteoarthritis and cartilage 25 (7), 1000-1009, 2017 | 114 | 2017 |
Mapping pathogenesis of arthritis through small animal models TL Vincent, RO Williams, R Maciewicz, A Silman, P Garside Rheumatology, 2012 | 100 | 2012 |
KATP Channel Gene Expression Is Induced by Urocortin and Mediates Its Cardioprotective Effect KM Lawrence, A Chanalaris, T Scarabelli, M Hubank, E Pasini, ... Circulation 106 (12), 1556-1562, 2002 | 93 | 2002 |
Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes A Chanalaris, KM Lawrence, A Stephanou, RD Knight, SY Hsu, ... Journal of Molecular and Cellular Cardiology 35 (10), 1295-1305, 2003 | 78 | 2003 |
CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy JM Zarebska, A Chanalaris, C Driscoll, A Burleigh, RE Miller, AM Malfait, ... Osteoarthritis and cartilage 25 (3), 406-412, 2017 | 58 | 2017 |
Cardioprotection mediated by urocortin is dependent upon PKCε activation KM Lawrence, AMN Kabir, M Bellahcene, S Davidson, RS Mesquita, ... The FASEB journal 19 (7), 1-18, 2005 | 57 | 2005 |
Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium insensitive phospholipase A2 gene expression KM Lawrence, TM Scarabelli, L Turtle, A Chanalaris, PA Townsend, ... The FASEB journal 17 (15), 2313-2315, 2003 | 57 | 2003 |
Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo KW Chong, A Chanalaris, A Burleigh, H Jin, FE Watt, J Saklatvala, ... Arthritis & Rheumatism 65 (9), 2346-2355, 2013 | 56 | 2013 |
Nociceptive sensitizers are regulated in damaged joint tissues, including articular cartilage, when osteoarthritic mice display pain behavior C Driscoll, A Chanalaris, C Knights, H Ismail, PK Sacitharan, C Gentry, ... Arthritis & Rheumatology 68 (4), 857-867, 2016 | 49 | 2016 |
Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis MD Gardiner, TL Vincent, C Driscoll, A Burleigh, G Bou-Gharios, ... Osteoarthritis and cartilage 23 (4), 616-628, 2015 | 47 | 2015 |
Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway A Chanalaris, KM Lawrence, PA Townsend, S Davidson, Y Jashmidi, ... Biochemical and biophysical research communications 328 (2), 442-448, 2005 | 45 | 2005 |
FISH mapping of Philadelphia negative BCR/ABL1 positive CML A Virgili, D Brazma, AG Reid, J Howard-Reeves, M Valgañón, ... Molecular Cytogenetics 1 (1), 1-13, 2008 | 43 | 2008 |
2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells AJ Steele, AG Prentice, AV Hoffbrand, BC Yogashangary, SM Hart, ... Blood 114 (6), 1217-1225, 2009 | 42 | 2009 |
Deletions of immunoglobulin heavy chain and T cell receptor gene regions are uniquely associated with lymphoid blast transformation of chronic myeloid leukemia EP Nacheva, D Brazma, A Virgili, J Howard-Reeves, A Chanalaris, ... BMC genomics 11 (1), 1-11, 2010 | 41 | 2010 |
SAG attenuates apoptotic cell death caused by simulated ischaemia/reoxygenation in rat cardiomyocytes A Chanalaris, Y Sun, DS Latchman, A Stephanou Journal of molecular and cellular cardiology 35 (3), 257-264, 2003 | 29 | 2003 |
Cyclic mechanical load causes global translational arrest in articular chondrocytes: a process which is partially dependent upon PKR phosphorylation C Lomas, XD Tang, A Chanalaris, J Saklatvala, TL Vincent Eur Cell Mater 22, 178-89, 2011 | 18 | 2011 |
Heparan sulfate proteoglycan synthesis is dysregulated in human osteoarthritic cartilage A Chanalaris, H Clarke, SE Guimond, TL Vincent, JE Turnbull, L Troeberg The American journal of pathology 189 (3), 632-647, 2019 | 14 | 2019 |
Generation of a mouse line harboring a bi‐transgene expressing luciferase and tamoxifen‐activatable creERT2 recombinase in cartilage LL Cascio, K Liu, H Nakamura, G Chu, NH Lim, A Chanalaris, ... genesis 52 (2), 110-119, 2014 | 14 | 2014 |
Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3 A Chanalaris, C Doherty, BD Marsden, G Bambridge, SP Wren, H Nagase, ... Molecular pharmacology 92 (4), 459-468, 2017 | 12 | 2017 |