| GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data BJ Schmidt, A Ebrahim, TO Metz, JN Adkins, BŲ Palsson, DR Hyduke Bioinformatics 29 (22), 2900-2908, 2013 | 132 | 2013 |
| Clinical Pharmacology Considerations for the Development of Immune Checkpoint Inhibitors J Sheng, S Srivastava, K Sanghavi, Z Lu, BJ Schmidt, AP Bello, M Gupta The Journal of Clinical Pharmacology 57 (S10), S26-S42, 2017 | 79 | 2017 |
| Alternate virtual populations elucidate the type I interferon signature predictive of the response to rituximab in rheumatoid arthritis BJ Schmidt, FP Casey, T Paterson, JR Chan BMC bioinformatics 14 (1), 221, 2013 | 56 | 2013 |
| Salmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes YM Kim, B Schmidt, A Kidwai, MB Jones, BLD Kaiser, HM Brewer, ... Mol. BioSyst. 9 (6), 1522-34, 2013 | 51 | 2013 |
| Mechanistic systems modeling to guide drug discovery and development BJ Schmidt, JA Papin, CJ Musante Drug Discovery Today 18 (3-4), 116-127, 2012 | 47 | 2012 |
| Metabolic systems analysis to advance algal biotechnology BJ Schmidt, X Lin‐Schmidt, A Chamberlin, K Salehi‐Ashtiani, JA Papin Biotechnology journal 5 (7), 660-670, 2010 | 41 | 2010 |
| Quantitative Systems Pharmacology: A Case for Disease Models CJ Musante, S Ramanujan, BJ Schmidt, OG Ghobrial, J Lu, ... Clin Pharmacol Ther 101 (1), 24-27, 2016 | 40 | 2016 |
| Adhesion and ultrasound-induced delivery from monodisperse microbubbles in a parallel plate flow cell BJ Schmidt, I Sousa, AA Van Beek, MR Bohmer Journal of Controlled Release 131 (1), 19-26, 2008 | 36 | 2008 |
| QSP Toolbox: Computational Implementation of Integrated Workflow Components for Deploying Multi-Scale Mechanistic Models Y Cheng, CJ Thalhauser, S Smithline, J Pagidala, M Miladinov, ... The AAPS Journal 19, 1002–1016, 2017 | 32 | 2017 |
| Model-based evaluation of the efficacy and safety of nivolumab once every 4 weeks across multiple tumor types X Zhao, J Shen, V Ivaturi, M Gopalakrishnan, Y Feng, BJ Schmidt, ... Annals of Oncology 31 (2), 302-309, 2020 | 25 | 2020 |
| Catch strip assay for the relative assessment of two-dimensional protein association kinetics BJ Schmidt, P Huang, KS Breuer, MB Lawrence Analytical chemistry 80 (4), 944-950, 2008 | 15 | 2008 |
| A survey of software tool utilization and capabilities for quantitative systems pharmacology: what we have and what we need S Ermakov, BJ Schmidt, CJ Musante, CJ Thalhauser CPT: pharmacometrics & systems pharmacology 8 (2), 62-76, 2018 | 14 | 2018 |
| Studying Salmonellae and Yersiniae Host-Pathogen Interactions Using Integrated'Omics and Modeling. C Ansong, BL Deatherage, D Hyduke, B Schmidt, JE McDermott, ... Current topics in microbiology and immunology, 2012 | 11 | 2012 |
| Nano-motion dynamics are determined by surface-tethered selectin mechanokinetics and bond formation BJ Schmidt, JA Papin, MB Lawrence PLoS computational biology 5 (12), e1000612, 2009 | 10 | 2009 |
| Development of a Quantitative Systems Pharmacology (QSP) Platform to Support Translational Research and Clinical Development of Affinity Drug Conjugates (ADCs) BJ Schmidt, HE Vezina, M Gupta, TA Leil J Pharmacokinet Pharmacodynam 42, S66-S67, 2015 | 7* | 2015 |
| FDA-Industry Scientific Exchange on assessing quantitative systems pharmacology models in clinical drug development: a meeting report, summary of challenges/gaps, and future … JPF Bai, BJ Schmidt, KG Gadkar, V Damian, JC Earp, C Friedrich, ... The AAPS Journal 23, 2021 | 6 | 2021 |
| Development of a quantitative systems pharmacology platform to support translational research and clinical development in immuno-oncology BJ Schmidt, DW Bartlett, S Agrawal, M Reed, M Jure-Kunkel, AA Gutierrez, ... ASCPT 2015 Annual Meeting, 2015 | 5 | 2015 |
| Mechanistic Predictions of Response to Combinations of Biologic Agents in a Quantitative Systems Pharmacology Model of Rheumatoid Arthritis CJ Thalhauser, BJ Schmidt, M Miladinov, TA Leil J Pharmacokinet Pharmacodynam 42, S38-S39, 2015 | 5 | 2015 |
| Systems biology for simulating patient physiology during the postgenomic era of medicine BJ Schmidt CPT: pharmacometrics & systems pharmacology 3 (3), 1-3, 2014 | 5 | 2014 |
| Nonclinical Pharmacology and Mechanistic Modeling of Antibody–Drug Conjugates in Support of Human Clinical Trials BJ Schmidt, C Pan, HE Vezina, H Sun, DD Leipold, M Gupta Antibody-Drug Conjugates: Fundamentals, Drug Development, and Clinical …, 2016 | 4 | 2016 |
Tarek A. LeilExecutive Director, Daiichi Sankyo, Inc.Verified email at dsi.com
