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Brian J. Schmidt
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GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data
BJ Schmidt, A Ebrahim, TO Metz, JN Adkins, BŲ Palsson, DR Hyduke
Bioinformatics 29 (22), 2900-2908, 2013
1322013
Clinical Pharmacology Considerations for the Development of Immune Checkpoint Inhibitors
J Sheng, S Srivastava, K Sanghavi, Z Lu, BJ Schmidt, AP Bello, M Gupta
The Journal of Clinical Pharmacology 57 (S10), S26-S42, 2017
792017
Alternate virtual populations elucidate the type I interferon signature predictive of the response to rituximab in rheumatoid arthritis
BJ Schmidt, FP Casey, T Paterson, JR Chan
BMC bioinformatics 14 (1), 221, 2013
562013
Salmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes
YM Kim, B Schmidt, A Kidwai, MB Jones, BLD Kaiser, HM Brewer, ...
Mol. BioSyst. 9 (6), 1522-34, 2013
512013
Mechanistic systems modeling to guide drug discovery and development
BJ Schmidt, JA Papin, CJ Musante
Drug Discovery Today 18 (3-4), 116-127, 2012
472012
Metabolic systems analysis to advance algal biotechnology
BJ Schmidt, X Lin‐Schmidt, A Chamberlin, K Salehi‐Ashtiani, JA Papin
Biotechnology journal 5 (7), 660-670, 2010
412010
Quantitative Systems Pharmacology: A Case for Disease Models
CJ Musante, S Ramanujan, BJ Schmidt, OG Ghobrial, J Lu, ...
Clin Pharmacol Ther 101 (1), 24-27, 2016
402016
Adhesion and ultrasound-induced delivery from monodisperse microbubbles in a parallel plate flow cell
BJ Schmidt, I Sousa, AA Van Beek, MR Bohmer
Journal of Controlled Release 131 (1), 19-26, 2008
362008
QSP Toolbox: Computational Implementation of Integrated Workflow Components for Deploying Multi-Scale Mechanistic Models
Y Cheng, CJ Thalhauser, S Smithline, J Pagidala, M Miladinov, ...
The AAPS Journal 19, 1002–1016, 2017
322017
Model-based evaluation of the efficacy and safety of nivolumab once every 4 weeks across multiple tumor types
X Zhao, J Shen, V Ivaturi, M Gopalakrishnan, Y Feng, BJ Schmidt, ...
Annals of Oncology 31 (2), 302-309, 2020
252020
Catch strip assay for the relative assessment of two-dimensional protein association kinetics
BJ Schmidt, P Huang, KS Breuer, MB Lawrence
Analytical chemistry 80 (4), 944-950, 2008
152008
A survey of software tool utilization and capabilities for quantitative systems pharmacology: what we have and what we need
S Ermakov, BJ Schmidt, CJ Musante, CJ Thalhauser
CPT: pharmacometrics & systems pharmacology 8 (2), 62-76, 2018
142018
Studying Salmonellae and Yersiniae Host-Pathogen Interactions Using Integrated'Omics and Modeling.
C Ansong, BL Deatherage, D Hyduke, B Schmidt, JE McDermott, ...
Current topics in microbiology and immunology, 2012
112012
Nano-motion dynamics are determined by surface-tethered selectin mechanokinetics and bond formation
BJ Schmidt, JA Papin, MB Lawrence
PLoS computational biology 5 (12), e1000612, 2009
102009
Development of a Quantitative Systems Pharmacology (QSP) Platform to Support Translational Research and Clinical Development of Affinity Drug Conjugates (ADCs)
BJ Schmidt, HE Vezina, M Gupta, TA Leil
J Pharmacokinet Pharmacodynam 42, S66-S67, 2015
7*2015
FDA-Industry Scientific Exchange on assessing quantitative systems pharmacology models in clinical drug development: a meeting report, summary of challenges/gaps, and future …
JPF Bai, BJ Schmidt, KG Gadkar, V Damian, JC Earp, C Friedrich, ...
The AAPS Journal 23, 2021
62021
Development of a quantitative systems pharmacology platform to support translational research and clinical development in immuno-oncology
BJ Schmidt, DW Bartlett, S Agrawal, M Reed, M Jure-Kunkel, AA Gutierrez, ...
ASCPT 2015 Annual Meeting, 2015
52015
Mechanistic Predictions of Response to Combinations of Biologic Agents in a Quantitative Systems Pharmacology Model of Rheumatoid Arthritis
CJ Thalhauser, BJ Schmidt, M Miladinov, TA Leil
J Pharmacokinet Pharmacodynam 42, S38-S39, 2015
52015
Systems biology for simulating patient physiology during the postgenomic era of medicine
BJ Schmidt
CPT: pharmacometrics & systems pharmacology 3 (3), 1-3, 2014
52014
Nonclinical Pharmacology and Mechanistic Modeling of Antibody–Drug Conjugates in Support of Human Clinical Trials
BJ Schmidt, C Pan, HE Vezina, H Sun, DD Leipold, M Gupta
Antibody-Drug Conjugates: Fundamentals, Drug Development, and Clinical …, 2016
42016
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