Shane Crotty
Shane Crotty
Professor, La Jolla Institute for Immunology
Verified email at - Homepage
Cited by
Cited by
Follicular Helper CD4 T Cells (TFH)
S Crotty
Annual review of immunology 29, 621-663, 2011
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
RJ Johnston, AC Poholek, D DiToro, I Yusuf, D Eto, B Barnett, AL Dent, ...
Science 325 (5943), 1006-1010, 2009
T follicular helper cell differentiation, function, and roles in disease
S Crotty
Immunity 41 (4), 529-542, 2014
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
S Crotty, D Maag, JJ Arnold, W Zhong, JYN Lau, Z Hong, R Andino, ...
Nature medicine 6 (12), 1375-1379, 2000
RNA virus error catastrophe: direct molecular test by using ribavirin
S Crotty, CE Cameron, R Andino
Proceedings of the National Academy of Sciences 98 (12), 6895-6900, 2001
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
YS Choi, R Kageyama, D Eto, TC Escobar, RJ Johnston, L Monticelli, ...
Immunity 34 (6), 932-946, 2011
Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals
A Grifoni, D Weiskopf, SI Ramirez, J Mateus, JM Dan, CR Moderbacher, ...
Cell, 2020
Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen
LJ Sigal, S Crotty, R Andino, KL Rock
Nature 398 (6722), 77-80, 1999
Cutting edge: long-term B cell memory in humans after smallpox vaccination
S Crotty, P Felgner, H Davies, J Glidewell, L Villarreal, R Ahmed
The Journal of Immunology 171 (10), 4969-4973, 2003
Resolution of a chronic viral infection after interleukin-10 receptor blockade
M Ejrnaes, CM Filippi, MM Martinic, EM Ling, LM Togher, S Crotty, ...
The Journal of experimental medicine 203 (11), 2461-2472, 2006
Human circulating PD-1+ CXCR3− CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses
M Locci, C Havenar-Daughton, E Landais, J Wu, MA Kroenke, ...
Immunity 39 (4), 758-769, 2013
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
S Crotty, RJ Johnston, SP Schoenberger
Nature immunology 11 (2), 114-120, 2010
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
D Eto, C Lao, D DiToro, B Barnett, TC Escobar, R Kageyama, I Yusuf, ...
PloS one 6 (3), e17739, 2011
SAP is required for generating long-term humoral immunity
S Crotty, EN Kersh, J Cannons, PL Schwartzberg, R Ahmed
Nature 421 (6920), 282-287, 2003
Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system
S Crotty, RD Aubert, J Glidewell, R Ahmed
Journal of immunological methods 286 (1-2), 111-122, 2004
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery
DH Davies, X Liang, JE Hernandez, A Randall, S Hirst, Y Mu, KM Romero, ...
Proceedings of the National Academy of Sciences 102 (3), 547-552, 2005
STAT5 is a potent negative regulator of TFH cell differentiation
RJ Johnston, YS Choi, JA Diamond, JA Yang, S Crotty
Journal of Experimental Medicine 209 (2), 243-250, 2012
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)
I Yusuf, R Kageyama, L Monticelli, RJ Johnston, D DiToro, K Hansen, ...
The Journal of Immunology 185 (1), 190-202, 2010
A brief history of T cell help to B cells
S Crotty
Nature Reviews Immunology 15 (3), 185-189, 2015
A blueprint for HIV vaccine discovery
DR Burton, R Ahmed, DH Barouch, ST Butera, S Crotty, A Godzik, ...
Cell host & microbe 12 (4), 396-407, 2012
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