Mark D. Biggin
Mark D. Biggin
Staff Scientist, Genomics Division, Lawrence Berkeley National Laboratory
Verified email at
Cited by
Cited by
Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination
MD Biggin, TJ Gibson, GF Hong
Proceedings of the National Academy of Sciences 80 (13), 3963-3965, 1983
DNA sequence and expression of the B95-8 Epstein-Barr virus genome.
R Baer, AT Bankier, MD Biggin, PL Deininger, PJ Farrell, TJ Gibson, ...
Nature, London 310, 207-211, 1984
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
YB Schwartz, TG Kahn, DA Nix, XY Li, R Bourgon, M Biggin, V Pirrotta
Nature genetics 38 (6), 700-705, 2006
Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
X Li, S MacArthur, R Bourgon, D Nix, DA Pollard, VN Iyer, A Hechmer, ...
PLoS biology 6 (2), e27, 2008
Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts
MD Biggin, R Tjian
Cell 53 (5), 699-711, 1988
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions
S MacArthur, XY Li, J Li, JB Brown, HC Chu, L Zeng, BP Grondona, ...
Genome biology 10 (7), 1-26, 2009
A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm
CC Fowlkes, CLL Hendriks, SVE Keränen, GH Weber, O Rübel, ...
Cell 133 (2), 364-374, 2008
Large-Scale Turnover of Functional Transcription Factor Binding Sites in Drosophila
AM Moses, DA Pollard, DA Nix, VN Iyer, XY Li, MD Biggin, MB Eisen
PLoS computational biology 2 (10), e130, 2006
Animal transcription networks as highly connected, quantitative continua
MD Biggin
Developmental cell 21 (4), 611-626, 2011
System wide analyses have underestimated protein abundances and the importance of transcription in mammals
JJ Li, PJ Bickel, MD Biggin
PeerJ 2, e270, 2014
Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome
Z Misulovin, YB Schwartz, XY Li, TG Kahn, M Gause, S MacArthur, JC Fay, ...
Chromosoma 117 (1), 89-102, 2008
NELF and GAGA Factor Are Linked to Promoter-Proximal Pausing at Many Genes in Drosophila
C Lee, X Li, A Hechmer, M Eisen, MD Biggin, BJ Venters, C Jiang, J Li, ...
Molecular and cellular biology 28 (10), 3290-3300, 2008
The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
XY Li, S Thomas, PJ Sabo, MB Eisen, JA Stamatoyannopoulos, ...
Genome biology 12 (4), 1-17, 2011
Binding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species
RK Bradley, XY Li, C Trapnell, S Davidson, L Pachter, HC Chu, LA Tonkin, ...
PLoS biology 8 (3), e1000343, 2010
Quantitative Models of the Mechanisms That Control Genome-Wide Patterns of Transcription Factor Binding during Early Drosophila Development
T Kaplan, XY Li, PJ Sabo, S Thomas, JA Stamatoyannopoulos, MD Biggin, ...
PLoS genetics 7 (2), e1001290, 2011
Dynamic reprogramming of chromatin accessibility during Drosophila embryo development
S Thomas, XY Li, PJ Sabo, R Sandstrom, RE Thurman, TK Canfield, ...
Genome biology 12 (5), 1-17, 2011
Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity
MD Biggin, W McGinnis
Development 124 (22), 4425-4433, 1997
Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells
M Biggin, M Bodescot, M Perricaudet, P Farrell
Journal of virology 61 (10), 3120-3132, 1987
A purified Drosophila homeodomain protein represses transcription in vitro
MD Biggin, R Tjian
Cell 58 (3), 433-440, 1989
Statistics requantitates the central dogma.
JJ Li, MD Biggin
Science 347 (6226), 1066-1067, 2015
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