|Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination|
MD Biggin, TJ Gibson, GF Hong
Proceedings of the National Academy of Sciences 80 (13), 3963-3965, 1983
|DNA sequence and expression of the B95-8 Epstein-Barr virus genome.|
R Baer, AT Bankier, MD Biggin, PL Deininger, PJ Farrell, TJ Gibson, ...
Nature, London 310, 207-211, 1984
|Genome-wide analysis of Polycomb targets in Drosophila melanogaster|
YB Schwartz, TG Kahn, DA Nix, XY Li, R Bourgon, M Biggin, V Pirrotta
Nature genetics 38 (6), 700-705, 2006
|Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm|
X Li, S MacArthur, R Bourgon, D Nix, DA Pollard, VN Iyer, A Hechmer, ...
PLoS Biol 6 (2), e27, 2008
|Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts|
MD Biggin, R Tjian
Cell 53 (5), 699-711, 1988
|Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions|
S MacArthur, XY Li, J Li, JB Brown, HC Chu, L Zeng, BP Grondona, ...
Genome biology 10 (7), 1-26, 2009
|A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm|
CC Fowlkes, CLL Hendriks, SVE Keränen, GH Weber, O Rübel, ...
Cell 133 (2), 364-374, 2008
|Large-scale turnover of functional transcription factor binding sites in Drosophila|
AM Moses, DA Pollard, DA Nix, VN Iyer, XY Li, MD Biggin, MB Eisen
PLoS Comput Biol 2 (10), e130, 2006
|Animal transcription networks as highly connected, quantitative continua|
Developmental cell 21 (4), 611-626, 2011
|System wide analyses have underestimated protein abundances and the importance of transcription in mammals|
JJ Li, PJ Bickel, MD Biggin
PeerJ 2, e270, 2014
|Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome|
Z Misulovin, YB Schwartz, XY Li, TG Kahn, M Gause, S MacArthur, JC Fay, ...
Chromosoma 117 (1), 89-102, 2008
|NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila|
C Lee, X Li, A Hechmer, M Eisen, MD Biggin, BJ Venters, C Jiang, J Li, ...
Molecular and cellular biology 28 (10), 3290-3300, 2008
|The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding|
XY Li, S Thomas, PJ Sabo, MB Eisen, JA Stamatoyannopoulos, ...
Genome biology 12 (4), 1-17, 2011
|Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species|
RK Bradley, XY Li, C Trapnell, S Davidson, L Pachter, HC Chu, LA Tonkin, ...
PLoS Biol 8 (3), e1000343, 2010
|Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development|
T Kaplan, XY Li, PJ Sabo, S Thomas, JA Stamatoyannopoulos, MD Biggin, ...
PLoS Genet 7 (2), e1001290, 2011
|Dynamic reprogramming of chromatin accessibility during Drosophila embryo development|
S Thomas, XY Li, PJ Sabo, R Sandstrom, RE Thurman, TK Canfield, ...
Genome biology 12 (5), 1-17, 2011
|Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity|
MD Biggin, W McGinnis
Development 124 (22), 4425-4433, 1997
|Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells.|
M Biggin, M Bodescot, M Perricaudet, P Farrell
Journal of virology 61 (10), 3120-3132, 1987
|Statistics requantitates the central dogma.|
JJ Li, MD Biggin
Science 347 (6226), 1066-1067, 2015
|A purified Drosophila homeodomain protein represses transcription in vitro|
MD Biggin, R Tjian
Cell 58 (3), 433-440, 1989