Thomas Litman
Thomas Litman
University of Copenhagen / LEO Pharma A/S
Verified email at - Homepage
Cited by
Cited by
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes
K Miyake, L Mickley, T Litman, Z Zhan, R Robey, B Cristensen, M Brangi, ...
Cancer research 59 (1), 8-13, 1999
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
T Litman, TE Druley, WD Stein, SE Bates
Cellular and Molecular Life Sciences CMLS 58, 931-959, 2001
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
T Litman, M Brangi, E Hudson, P Fetsch, A Abati, DD Ross, K Miyake, ...
Journal of cell science 113 (11), 2011-2021, 2000
Channels, carriers, and pumps: an introduction to membrane transport
WD Stein, T Litman
Elsevier, 2014
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
Y Honjo, CA Hrycyna, QW Yan, WY Medina-Pérez, RW Robey, ...
Cancer research 61 (18), 6635-6639, 2001
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells
RW Robey, WY Medina-Pérez, K Nishiyama, T Lahusen, K Miyake, ...
Clinical Cancer Research 7 (1), 145-152, 2001
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells
C Özvegy, T Litman, G Szakács, Z Nagy, S Bates, A Váradi, B Sarkadi
Biochemical and biophysical research communications 285 (1), 111-117, 2001
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
M de Bruin, K Miyake, T Litman, R Robey, SE Bates
Cancer letters 146 (2), 117-126, 1999
The effect of short-chain fatty acids on human monocyte-derived dendritic cells
C Nastasi, M Candela, CM Bonefeld, C Geisler, M Hansen, T Krejsgaard, ...
Scientific reports 5 (1), 16148, 2015
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
M Brangi, T Litman, M Ciotti, K Nishiyama, G Kohlhagen, C Takimoto, ...
Cancer research 59 (23), 5938-5946, 1999
Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer
ES Martens-Uzunova, SE Jalava, NF Dits, G Van Leenders, S Mřller, ...
Oncogene 31 (8), 978-991, 2012
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
RW Robey, Y Honjo, A van de Laar, K Miyake, JT Regis, T Litman, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1512 (2), 171-182, 2001
Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)
U Ralfkiaer, PH Hagedorn, N Bangsgaard, MB Lřvendorf, CB Ahler, ...
Blood, The Journal of the American Society of Hematology 118 (22), 5891-5900, 2011
Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
PA Fetsch, A Abati, T Litman, K Morisaki, Y Honjo, K Mittal, SE Bates
Cancer letters 235 (1), 84-92, 2006
The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
E Rocchi, A Khodjakov, EL Volk, CH Yang, T Litman, SE Bates, ...
Biochemical and biophysical research communications 271 (1), 42-46, 2000
MicroRNAs and potential target interactions in psoriasis
JR Zibert, MB Lřvendorf, T Litman, J Olsen, B Kaczkowski, L Skov
Journal of dermatological science 58 (3), 177-185, 2010
Measurement of cell volume changes by fluorescence self-quenching
S Hamann, JF Kiilgaard, T Litman, FJ Alvarez-Leefmans, BR Winther, ...
Journal of fluorescence 12, 139-145, 2002
Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity.
T Litman, T Zeuthen, T Skovsgaard, WD Stein
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1361 (2), 169-176, 1997
Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity
T Litman, T Zeuthen, T Skovsgaard, WD Stein
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1361 (2), 159-168, 1997
Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection
H Esaki, DA Ewald, B Ungar, M Rozenblit, X Zheng, H Xu, YD Estrada, ...
Journal of Allergy and Clinical Immunology 135 (1), 153-163, 2015
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