Alain de Bruin
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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA
M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ...
Developmental cell 31 (6), 722-733, 2014
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ...
Cancer discovery 7 (2), 165-176, 2017
Direct evidence for epithelial-mesenchymal transitions in breast cancer
AJ Trimboli, K Fukino, A de Bruin, G Wei, L Shen, SM Tanner, N Creasap, ...
Cancer research 68 (3), 937-945, 2008
Extra-embryonic function of Rb is essential for embryonic development and viability
L Wu, A de Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ...
Nature 421 (6926), 942-947, 2003
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling
PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ...
Nature cell biology 12 (12), 1220-1227, 2010
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation
A de Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone
Journal of Biological Chemistry 278 (43), 42041-42049, 2003
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation
B Maiti, J Li, A De Bruin, F Gordon, C Timmers, R Opavsky, K Patil, J Tuttle, ...
Journal of Biological Chemistry 280 (18), 18211-18220, 2005
In vivo biocompatibility and biodegradation of 3D-printed porous scaffolds based on a hydroxyl-functionalized poly (-caprolactone)
H Seyednejad, D Gawlitta, RV Kuiper, A de Bruin, CF van Nostrum, ...
Biomaterials 33 (17), 4309-4318, 2012
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development
J Li, C Ran, E Li, F Gordon, G Comstock, H Siddiqui, W Cleghorn, ...
Developmental cell 14 (1), 62-75, 2008
A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris
R Caldelari, A De Bruin, D Baumann, MM Suter, C Bierkamp, V Balmer, ...
The Journal of cell biology 153 (4), 823-834, 2001
Pemphigus vulgaris identifies plakoglobin as key suppressor of c‐Myc in the skin
L Williamson, NA Raess, R Caldelari, A Zakher, A de Bruin, H Posthaus, ...
The EMBO journal 25 (14), 3298-3309, 2006
Interferon- impairs proliferation of hematopoietic stem cells in mice
AM de Bruin, Ö Demirel, B Hooibrink, CH Brandts, MA Nolte
Blood, The Journal of the American Society of Hematology 121 (18), 3578-3585, 2013
High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice
RA van der Heijden, F Sheedfar, MC Morrison, PPH Hommelberg, D Kor, ...
Aging (Albany NY) 7 (4), 256, 2015
Chronic IFN- production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU. 1 axis
SF Libregts, L Gutiérrez, AM de Bruin, FM Wensveen, P Papadopoulos, ...
Blood, The Journal of the American Society of Hematology 118 (9), 2578-2588, 2011
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice
A de Bruin, L Wu, HI Saavedra, P Wilson, Y Yang, TJ Rosol, M Weinstein, ...
Proceedings of the National Academy of Sciences 100 (11), 6546-6551, 2003
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ...
Nature 537 (7620), 427-431, 2016
Essential role for survivin in early brain development
Y Jiang, A De Bruin, H Caldas, J Fangusaro, J Hayes, EM Conway, ...
Journal of Neuroscience 25 (30), 6962-6970, 2005
Impact of interferon- on hematopoiesis
AM de Bruin, C Voermans, MA Nolte
Blood, The Journal of the American Society of Hematology 124 (16), 2479-2486, 2014
IFN induces monopoiesis and inhibits neutrophil development during inflammation
AM de Bruin, SF Libregts, M Valkhof, L Boon, IP Touw, MA Nolte
Blood, The Journal of the American Society of Hematology 119 (6), 1543-1554, 2012
Physiological significance of polyploidization in mammalian cells
SK Pandit, B Westendorp, A de Bruin
Trends in cell biology 23 (11), 556-566, 2013
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