| Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure− activity relationships, and X-ray crystallographic studies X Wen, H Sun, J Liu, K Cheng, P Zhang, L Zhang, J Hao, L Zhang, P Ni, ... Journal of Medicinal Chemistry 51 (12), 3540-3554, 2008 | 254 | 2008 |
| New inhibitors of glycogen phosphorylase as potential antidiabetic agents L Somsák, K Czifrák, M Tóth, E Bokor, ED Chrysina, KM Alexacou, ... Current medicinal chemistry 15 (28), 2933-2983, 2008 | 224 | 2008 |
| Potent inhibition of glycogen phosphorylase by a spirohydantoin of glucopyranose: First pyranose analogues of hydantocidin CJF Bichard, EP Mitchell, MR Wormald, KA Watson, LN Johnson, ... Tetrahedron letters 36 (12), 2145-2148, 1995 | 182 | 1995 |
| Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site NG Oikonomakos, JB Schnier, SE Zographos, VT Skamnaki, ... Journal of Biological Chemistry 275 (44), 34566-34573, 2000 | 172 | 2000 |
| Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents KE Tsitsanou, T Thireou, CE Drakou, K Koussis, MV Keramioti, ... Cellular and Molecular Life Sciences 69, 283-297, 2012 | 130 | 2012 |
| Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection KA Watson, EP Mitchell, LN Johnson, G Cruciani, JC Son, CJF Bichard, ... Acta Crystallographica Section D: Biological Crystallography 51 (4), 458-472, 1995 | 126 | 1995 |
| Kinetics, in silico docking, molecular dynamics, and MM‐GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP … JM Hayes, VT Skamnaki, G Archontis, C Lamprakis, J Sarrou, N Bischler, ... Proteins: Structure, Function, and Bioinformatics 79 (3), 703-719, 2011 | 112 | 2011 |
| The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor SE Zographos, NG Oikonomakos, KE Tsitsanou, DD Leonidas, ... Structure 5 (11), 1413-1425, 1997 | 112 | 1997 |
| Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors M Benltifa, JM Hayes, S Vidal, D Gueyrard, PG Goekjian, JP Praly, ... Bioorganic & medicinal chemistry 17 (20), 7368-7380, 2009 | 100 | 2009 |
| Amide-1, 2, 3-triazole bioisosterism: the glycogen phosphorylase case ED Chrysina, É Bokor, KM Alexacou, MD Charavgi, GN Oikonomakos, ... Tetrahedron: Asymmetry 20 (6-8), 733-740, 2009 | 99 | 2009 |
| Binding of N‐acetyl‐N ′‐β‐d‐glucopyranosyl urea and N‐benzoyl‐N ′‐β‐d‐glucopyranosyl urea to glycogen phosphorylase b Kinetic and … NG Oikonomakos, M Kosmopoulou, SE Zographos, DD Leonidas, ... European journal of biochemistry 269 (6), 1684-1696, 2002 | 98 | 2002 |
| N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose NG Oikonomakos, M Kontou, SE Zographos, KA Watson, LN Johnson, ... Protein Science 4 (12), 2469-2477, 1995 | 94 | 1995 |
| Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition NG Oikonomakos, C Tiraidis, DD Leonidas, SE Zographos, M Kristiansen, ... Journal of medicinal chemistry 49 (19), 5687-5701, 2006 | 91 | 2006 |
| Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1, 4-dihydro-1-ethyl-2-methyl-pyridine-3, 5, 6-tricarboxylate NG Oikonomakos, KE Tsitsanou, SE Zographos, VT Skamnaki, ... Protein Science 8 (10), 1930-1945, 1999 | 75 | 1999 |
| Cooperative Interactions of the Catalytic Nucleophile and the Catalytic Acid in the Inhibition of β‐Glycosidases. Calculations and their validation by comparative kinetic and … TD Heightman, A Vasella, KE Tsitsanou, SE Zographos, VT Skamnaki, ... Helvetica chimica acta 81 (5‐8), 853-864, 1998 | 74 | 1998 |
| Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate TM Krülle, C de la Fuente, L Pickering, RT Aplin, KE Tsitsanou, ... Tetrahedron: Asymmetry 8 (22), 3807-3820, 1997 | 74 | 1997 |
| 1-(3-Deoxy-3-fluoro-β-D-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies VG Tsirkone, E Tsoukala, C Lamprakis, S Manta, JM Hayes, VT Skamnaki, ... Bioorganic & medicinal chemistry 18 (10), 3413-3425, 2010 | 69 | 2010 |
| Specific inhibition of glycogen phosphorylase by a spirodiketopiperazine at the anomeric position of glucopyranose TM Krülle, KA Watson, M Gregoriou, LN Johnson, S Crook, DJ Watkin, ... Tetrahedron letters 36 (45), 8291-8294, 1995 | 64 | 1995 |
| The σ‐Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen … AL Kantsadi, JM Hayes, S Manta, VT Skamnaki, C Kiritsis, AMG Psarra, ... ChemMedChem 7 (4), 722-732, 2012 | 63 | 2012 |
| Differential expression of molecular motors in the motor cortex of sporadic ALS M Pantelidou, SE Zographos, CW Lederer, T Kyriakides, MW Pfaffl, ... Neurobiology of Disease 26 (3), 577-589, 2007 | 58 | 2007 |
