| A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis QH Ma, T Futagawa, WL Yang, XD Jiang, L Zeng, Y Takeda, RX Xu, ... Nature cell biology 10 (3), 283-294, 2008 | 242 | 2008 |
| S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response KP Lai, WF Leong, JFL Chau, D Jia, L Zeng, H Liu, L He, A Hao, H Zhang, ... The EMBO journal 29 (17), 2994-3006, 2010 | 124 | 2010 |
| microRNAs and neurodegenerative diseases L Qiu, EK Tan, L Zeng microRNA: Medical Evidence: From Molecular Biology to Clinical Practice, 85-105, 2015 | 112 | 2015 |
| Chronic cerebral hypoperfusion enhances Tau hyperphosphorylation and reduces autophagy in AlzheimerĒs disease mice L Qiu, G Ng, EK Tan, P Liao, N Kandiah, L Zeng Scientific reports 6 (1), 23964, 2016 | 101 | 2016 |
| Nogo‐A at CNS paranodes is a ligand of Caspr: possible regulation of K+ channel localization DY Nie, ZH Zhou, BT Ang, FYH Teng, G Xu, T Xiang, C Wang, L Zeng, ... The EMBO journal, 2003 | 85 | 2003 |
| Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis L Zeng, GZ Wu, KJ Goh, YM Lee, CC Ng, AB You, J Wang, D Jia, A Hao, ... PloS one 3 (6), e2329, 2008 | 76 | 2008 |
| MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex W Zhang, PJ Kim, Z Chen, H Lokman, L Qiu, K Zhang, SG Rozen, EK Tan, ... Elife 5, e11324, 2016 | 74 | 2016 |
| Non-motor and motor features in LRRK2 transgenic mice Z Bichler, HC Lim, L Zeng, EK Tan PloS one 8 (7), e70249, 2013 | 65 | 2013 |
| Amyloid precursor protein regulates neurogenesis by antagonizing miR-574-5p in the developing cerebral cortex W Zhang, S Thevapriya, PJ Kim, WP Yu, H Shawn Je, E King Tan, L Zeng Nature communications 5 (1), 3330, 2014 | 57 | 2014 |
| Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in ParkinsonĒs disease ZC Chen, W Zhang, LL Chua, C Chai, R Li, L Lin, Z Cao, DC Angeles, ... Science signaling 10 (488), eaam6790, 2017 | 50 | 2017 |
| Deciphering the function and regulation of microRNAs in AlzheimerĒs disease and ParkinsonĒs disease L Qiu, W Zhang, EK Tan, L Zeng ACS chemical neuroscience 5 (10), 884-894, 2014 | 48 | 2014 |
| Higher peripheral TREM2 mRNA levels relate to cognitive deficits and hippocampal atrophy in AlzheimerĒs disease and amnestic mild cognitive impairment YJ Tan, ASL Ng, A Vipin, JKW Lim, RJ Chander, F Ji, Y Qiu, SKS Ting, ... Journal of Alzheimer's Disease 58 (2), 413-423, 2017 | 45 | 2017 |
| Single-cell transcriptomics and surface epitope detection in human brain epileptic lesions identifies pro-inflammatory signaling P Kumar, A Lim, SN Hazirah, CJH Chua, A Ngoh, SL Poh, TH Yeo, J Lim, ... Nature Neuroscience 25 (7), 956-966, 2022 | 36 | 2022 |
| Modelling Alzheimer's disease: Insights from in vivo to in vitro three‐dimensional culture platforms VD Ranjan, L Qiu, EK Tan, L Zeng, Y Zhang Journal of tissue engineering and regenerative medicine 12 (9), 1944-1958, 2018 | 33 | 2018 |
| Current status of stem cell-derived therapies for ParkinsonĒs disease: from cell assessment and imaging modalities to clinical trials SE Jang, L Qiu, LL Chan, EK Tan, L Zeng Frontiers in neuroscience 14, 558532, 2020 | 32 | 2020 |
| Immature midbrain dopaminergic neurons derived from floor-plate method improve cell transplantation therapy efficacy for Parkinson's disease L Qiu, MC Liao, AK Chen, S Wei, S Xie, S Reuveny, ZD Zhou, W Hunziker, ... Stem cells translational medicine 6 (9), 1803-1814, 2017 | 32 | 2017 |
| A potential role for protein palmitoylation and zDHHC16 in DNA damage response N Cao, JK Li, YQ Rao, H Liu, J Wu, B Li, P Zhao, L Zeng, J Li BMC molecular biology 17, 1-11, 2016 | 32 | 2016 |
| In utero infection of Zika virus leads to abnormal central nervous system development in mice W Zhang, YW Tan, WK Yam, H Tu, L Qiu, EK Tan, JJH Chu, L Zeng Scientific reports 9 (1), 7298, 2019 | 25 | 2019 |
| LRRK2 interacts with ATM and regulates Mdm2–p53 cell proliferation axis in response to genotoxic stress Z Chen, Z Cao, W Zhang, M Gu, ZD Zhou, B Li, J Li, EK Tan, L Zeng Human molecular genetics 26 (22), 4494-4505, 2017 | 25 | 2017 |
| Altered cerebrospinal fluid exosomal microRNA levels in young-onset AlzheimerĒs disease and frontotemporal dementia YJ Tan, BYX Wong, R Vaidyanathan, S Sreejith, SY Chia, N Kandiah, ... Journal of Alzheimer's Disease Reports 5 (1), 805-813, 2021 | 24 | 2021 |
Adeline NgSenior Consultant NeurologistVerified email at singhealth.com.sg
