Howard McLeod
Howard McLeod
Medical Director, Geriatric Oncology Consortium
Verified email at the-goc.org - Homepage
Title
Cited by
Cited by
Year
Pharmacogenomics—drug disposition, drug targets, and side effects
WE Evans, HL McLeod
New England Journal of Medicine 348 (6), 538-549, 2003
22342003
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
MJ Rieder, AP Reiner, BF Gage, DA Nickerson, CS Eby, HL McLeod, ...
New England Journal of Medicine 352 (22), 2285-2293, 2005
16562005
Doxorubicin pathways: pharmacodynamics and adverse effects
CF Thorn, C Oshiro, S Marsh, T Hernandez-Boussard, H McLeod, ...
Pharmacogenetics and genomics 21 (7), 440, 2011
9782011
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
BF Gage, C Eby, JA Johnson, E Deych, MJ Rieder, PM Ridker, ...
Clinical Pharmacology & Therapeutics 84 (3), 326-331, 2008
8292008
Genomics and drug response
L Wang, HL McLeod, RM Weinshilboum
New England Journal of Medicine 364 (12), 1144-1153, 2011
6192011
MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity
MM Ameyaw, F Regateiro, T Li, X Liu, M Tariq, A Mobarek, N Thornton, ...
Pharmacogenetics and Genomics 11 (3), 217-221, 2001
5592001
Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer
Y Wang, T Jatkoe, Y Zhang, MG Mutch, D Talantov, J Jiang, HL McLeod, ...
Journal of clinical oncology 22 (9), 1564-1571, 2004
5332004
Platinum neurotoxicity pharmacogenetics
SR McWhinney, RM Goldberg, HL McLeod
Molecular cancer therapeutics 8 (1), 10-16, 2009
5152009
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
HL McLeod, EY Krynetski, MV Relling, WE Evans
Leukemia 14 (4), 567-572, 2000
5052000
UGT1A1* 28 genotype and irinotecan-induced neutropenia: dose matters
JM Hoskins, RM Goldberg, P Qu, JG Ibrahim, HL McLeod
Journal of the National Cancer Institute 99 (17), 1290-1295, 2007
5032007
Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs
S Zhou, SY Chan, BC Goh, E Chan, W Duan, M Huang, HL McLeod
Clinical pharmacokinetics 44 (3), 279-304, 2005
5032005
PI3K/Akt/mTOR pathway as a target for cancer therapy
D Morgensztern, HL McLeod
Anti-cancer drugs 16 (8), 797-803, 2005
4662005
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
AJ Black, HL McLeod, HA Capell, RH Powrie, LK Matowe, SC Pritchard, ...
Annals of internal medicine 129 (9), 716-718, 1998
4521998
Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.
X Wei, HL McLeod, J McMurrough, FJ Gonzalez, P Fernandez-Salguero
The Journal of clinical investigation 98 (3), 610-615, 1996
4281996
The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations
ESR Collie-Duguid, J Sludden, T Li, HL McLeod
Pharmacogenetics and Genomics 9 (1), 37-42, 1999
4061999
Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin
BF Gage, C Eby, PE Milligan, GA Banet, JR Duncan, HL McLeod
Thrombosis and haemostasis 91 (01), 87-94, 2004
4042004
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
GJ Peters, HHJ Backus, S Freemantle, B Van Triest, G Codacci-Pisanelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1587 (2-3 …, 2002
3882002
PHARMACOGENOMICS: Unlocking the Human Genome for Better Drug Therapy
HL McLeod, WE Evans
Annual review of pharmacology and toxicology 41 (1), 101-121, 2001
3802001
Strategies for enzyme/prodrug cancer therapy
G Xu, HL McLeod
Clinical Cancer Research 7 (11), 3314-3324, 2001
3612001
Carbamazepine, HLA-B*1502 and risk of Stevens–Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations
PB Ferrell, HL McLeod
Future Medicine Ltd 9 (10), 1543-1546, 2008
3582008
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Articles 1–20