miR-34 miRNAs provide a barrier for somatic cell reprogramming YJ Choi, CP Lin, JJ Ho, X He, N Okada, P Bu, Y Zhong, SY Kim, ... Nature cell biology 13 (11), 1353-1360, 2011 | 449 | 2011 |
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells P Bu, KY Chen, JH Chen, L Wang, J Walters, YJ Shin, JP Goerger, J Sun, ... Cell stem cell 12 (5), 602-615, 2013 | 393 | 2013 |
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression N Okada, CP Lin, MC Ribeiro, A Biton, G Lai, X He, P Bu, H Vogel, ... Genes & development 28 (5), 438-450, 2014 | 317 | 2014 |
Targeted drug delivery to circulating tumor cells via platelet membrane-functionalized particles J Li, Y Ai, L Wang, P Bu, CC Sharkey, Q Wu, B Wun, S Roy, X Shen, ... Biomaterials 76, 52-65, 2016 | 274 | 2016 |
Non-coding RNA in cancer H Yan, P Bu Essays in biochemistry 65 (4), 625-639, 2021 | 250 | 2021 |
Aldolase B-mediated fructose metabolism drives metabolic reprogramming of colon cancer liver metastasis P Bu, KY Chen, K Xiang, C Johnson, SB Crown, N Rakhilin, Y Ai, L Wang, ... Cell metabolism 27 (6), 1249-1262. e4, 2018 | 228 | 2018 |
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation S Sun, G Shi, H Sha, Y Ji, X Han, X Shu, H Ma, T Inoue, B Gao, H Kim, ... Nature cell biology 17 (12), 1546-1555, 2015 | 200 | 2015 |
A miR-34a-numb feedforward loop triggered by inflammation regulates asymmetric stem cell division in intestine and colon cancer P Bu, L Wang, KY Chen, T Srinivasan, PKL Murthy, KL Tung, AK Varanko, ... Cell stem cell 18 (2), 189-202, 2016 | 149 | 2016 |
A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division L Wang, P Bu, Y Ai, T Srinivasan, HJ Chen, K Xiang, SM Lipkin, X Shen Elife 5, e14620, 2016 | 131 | 2016 |
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β P Bu, L Wang, KY Chen, N Rakhilin, J Sun, A Closa, KL Tung, S King, ... Nature communications 6 (1), 6879, 2015 | 127 | 2015 |
A recellularized human colon model identifies cancer driver genes HJ Chen, Z Wei, J Sun, A Bhattacharya, DJ Savage, R Serda, Y Mackeyev, ... Nature biotechnology 34 (8), 845-851, 2016 | 99 | 2016 |
Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis HJ Chen, R Edwards, S Tucci, P Bu, J Milsom, S Lee, W Edelmann, ... The Journal of clinical investigation 122 (9), 3184-3196, 2012 | 91 | 2012 |
N6-methyladenosine modification of MALAT1 promotes metastasis via reshaping nuclear speckles X Wang, C Liu, S Zhang, H Yan, L Zhang, A Jiang, Y Liu, Y Feng, D Li, ... Developmental cell 56 (5), 702-715. e8, 2021 | 85 | 2021 |
Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-κB activation P Bu, L Gao, J Zhuang, J Feng, D Yang, X Yan Molecular cancer therapeutics 5 (11), 2872-2878, 2006 | 84 | 2006 |
Creatine promotes cancer metastasis through activation of Smad2/3 L Zhang, Z Zhu, H Yan, W Wang, Z Wu, F Zhang, Q Zhang, G Shi, J Du, ... Cell metabolism 33 (6), 1111-1123. e4, 2021 | 69 | 2021 |
Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis Y Xu, L Wang, MD Zimmerman, KY Chen, L Huang, DJ Fu, F Kaya, ... PLoS pathogens 14 (4), e1006974, 2018 | 64 | 2018 |
NOTCH signaling regulates asymmetric cell fate of fast-and slow-cycling colon cancer–initiating cells T Srinivasan, J Walters, P Bu, EB Than, KL Tung, KY Chen, N Panarelli, ... Cancer research 76 (11), 3411-3421, 2016 | 61 | 2016 |
Non-coding RNAs in cancer stem cells H Yan, P Bu Cancer letters 421, 121-126, 2018 | 51 | 2018 |
Visualization of CD146 dimerization and its regulation in living cells P Bu, J Zhuang, J Feng, D Yang, X Shen, X Yan Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (4), 513-520, 2007 | 50 | 2007 |
A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal KY Chen, T Srinivasan, KL Tung, JM Belmonte, L Wang, PKL Murthy, ... Molecular Systems Biology 13 (4), 927, 2017 | 48 | 2017 |